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Regulation of JNK Signaling by GSTp
Studies of low basal Jun N-terminal kinase (JNK) activity in non-stressed cells led us to identify a JNK inhibitor that was purified and identified as glutathione S-transferase Pi (GSTp) and was characterized as a JNK-associated protein.
Colin J Henderson +2 more
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The JNK Signal Transduction Pathway
Current Opinion in Genetics and Development, 2002The c-Jun NH(2)-terminal kinases (JNKs) are an evolutionarily conserved sub-group of mitogen-activated protein (MAP) kinases. Recent studies have improved our understanding of the physiological function of the JNK pathway. Roles of novel molecules that participate in the JNK pathway have been defined and new insight into the role of JNK in survival ...
Roger John Davis
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Science Signaling, 2009
The mutant Huntingtin protein inhibits fast axonal transport by activating a JNK isoform that is enriched in brain.
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The mutant Huntingtin protein inhibits fast axonal transport by activating a JNK isoform that is enriched in brain.
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JNK: a killer on a transcriptional leash
Cell Death & Differentiation, 2003Whether to live or die is arguably the most important decision a cell has to make, and the NF-B/Rel group of transcription factors is a key element in this decision. Since the discovery of the Anti-Apoptotic Function of NF-B in 1996, the number of publications dealing with the control of apoptosis by NF-B has increased at an astonishing pace – over 600
FRANZOSO G +2 more
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