Results 171 to 180 of about 161,447 (312)
Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence
Cancer Innovation, Volume 5, Issue 1, February 2026.Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley +1 more source
Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar +5 more
wiley +1 more source
Cellular signaling pathways of matrix metalloproteinase gene expression by Pseudomonas aeruginosa-infected human bronchial epithelial cells [PDF]
, 2014 Research Dissemination Reports - supported by funds (Research Fund for the Control of Infectious Diseases ...
Ho, PL +4 more
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Molecular Mechanisms and Therapeutic Potential of DJ‐1 in Skeletal Muscle Homeostasis and Disease
Comprehensive Physiology, Volume 16, Issue 1, February 2026.DJ‐1 protein functions as a redox‐sensing guardian in skeletal muscle by coordinating antioxidant defense, mitochondrial homeostasis, metabolic adaptation, and anti‐atrophy signaling. Enhancing its function holds promise as a potential therapeutic strategy for muscle atrophy, ALS, and metabolic myopathies.
Yue Zhang +5 more
wiley +1 more source
Hypercapnia Effects on Lung Function
Comprehensive Physiology, Volume 16, Issue 1, February 2026.CO2 is a signaling molecule that disrupts alveolar fluid clearance and ion transport, impairs alveolar repair, and promotes mitochondrial and endoplasmic reticulum dysfunction. It suppresses innate immunity, host defense, and inflammation, while increasing airway contractility.
Seungseo Choi +2 more
wiley +1 more source
CEACAM6 silencing suppresses tumour growth and sensitises cholangiocarcinoma to cisplatin
Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.CEACAM6 has the potential to become a novel and independent prognostic biomarker in cholangiocarcinoma (CCA). Silencing CEACAM6 can inhibit CCA tumour growth and significantly enhance the chemosensitivity to cisplatin. This chemo‐sensitising effect is mediated through the disruption of ribosome biogenesis and impairment of DNA damage repair.
Shi‐Jia Dai +8 more
wiley +1 more source
Mitogen-activated protein kinase kinase kinase 12 (MAP3K12; DLK); c-jun N-terminal kinase (JNK) [PDF]
Science-Business eXchange, 2009 openaire +1 more source
eFood, Volume 7, Issue 1, February 2026.Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram +6 more
wiley +1 more source
Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation
Food Science &Nutrition, Volume 14, Issue 2, February 2026.Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid +7 more
wiley +1 more source