Results 171 to 180 of about 167,044 (343)

Stress and Vascular Responses: Atheroprotective Effect of Laminar Fluid Shear Stress in Endothelial Cells: Possible Role of Mitogen-Activated Protein Kinases

open access: yesJournal of Pharmacological Sciences, 2003
Atherosclerosis preferentially occurs in areas of turbulent blood flow and low fluid shear stress, whereas laminar blood flow and high shear stress are atheroprotective.
Masanori Yoshizumi   +4 more
doaj  

MD and EPR studies of the structure and dynamics of the MTSL spin-labelled activation loop of the Aurora-A kinase [PDF]

open access: yesarXiv, 2015
The understanding of kinase structure is mostly based on protein crystallography, which is limited by the requirement to trap molecules within a crystal lattice. Therefore, characterisations of the conformational dynamics of the activation loop in solution are important to enhance the understanding of molecular processes related to diseases and to ...
arxiv  

Targeting of p38 Mitogen-Activated Protein Kinases to MEF2 Transcription Factors

open access: yesMolecular and Cellular Biology, 1999
Mitogen-activated protein (MAP) kinase-mediated signalling to the nucleus is an important event in the conversion of extracellular signals into a cellular response.
Shen-hsi Yang   +2 more
semanticscholar   +1 more source

The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]

open access: yes, 2009
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J.   +7 more
core   +1 more source

Differential activation of mitogen-activated protein kinases in AGS gastric epithelial cells by cag+ and cag- Helicobacter pylori.

open access: yesJournal of Immunology, 1999
The aim of this study was to determine whether Helicobacter pylori activates mitogen-activated protein (MAP) kinases in gastric epithelial cells. Infection of AGS cells with an H.
S. Keates   +5 more
semanticscholar   +1 more source

Differential expression of mitogen activating protein kinases in periodontitis [PDF]

open access: yes, 2013
Aim Following toll‐like receptor ( TLR ) engagement, lipopolysaccharide ( LPS ) can stimulate the expression of pro‐inflammatory cytokines thus activating the innate immune response.
D'Silva, Nisha J.   +4 more
core   +1 more source

Latent periodicity of serine-threonine and tyrosine protein kinases and another protein families [PDF]

open access: yesMolekularnuya Biologiya (Russian), vol.39, N3, 2005, 2004
We identified latent periodicity in catalytic domains of approximately 85% of serine/threonine and tyrosine protein kinases. Similar results were obtained for other 22 protein domains. We also designed the method of noise decomposition, which is aimed to distinguish between different periodicity types of the same period length. The method is to be used
arxiv  

Dual p38/JNK Mitogen Activated Protein Kinase Inhibitors Prevent Ozone-Induced Airway Hyperreactivity in Guinea Pigs

open access: yesPLoS ONE, 2013
Ozone exposure causes airway hyperreactivity and increases hospitalizations resulting from pulmonary complications. Ozone reacts with the epithelial lining fluid and airway epithelium to produce reactive oxygen species and lipid peroxidation products, which then activate cell signaling pathways, including the mitogen activated protein kinase (MAPK ...
Mark W. Ledeboer   +5 more
openaire   +4 more sources

Ferulic acid: extraction, estimation, bioactivity and applications for human health and food

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar   +13 more
wiley   +1 more source

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