Results 191 to 200 of about 79,924 (277)

MAP3K1: A Multifunctional Kinase at the Crossroads of Cancer Progression and Tumor Suppression. [PDF]

Cells
Umeta LT, Natarajan A.
europepmc   +1 more source

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang, Zengkan Du, Ping Lu, Aimin Jiang, Yadong Guo, Yawei Liu, Zhijing Song, Bing Dai, Wangzheqi Zhang   +8 more
wiley   +1 more source

Phosphoproteome-Entailed Kinase-Substrate Landscape of Human-DENV-2 Interaction. [PDF]

Int J Mol Sci
Jabbar AA, Shaji V, Anil A, Nisar M, Soman S, Prasad G, Abhinand CS, Modi PK, Madanan MG, Jayanandan A, Pilankatta R, Raju R.   +11 more
europepmc   +1 more source

Vitamin K2 Extends Lifespan by Alleviating Mitochondrial Stress via the JNK‐1/SIR‐2.1/DAF‐16 Signaling Axis in Caenorhabditis elegans

Aging Cell, Volume 25, Issue 5, May 2026.
Vitamin K2 activates the JNK‐1/SIR‐2.1/DAF‐16 signaling axis in C. elegans, alleviating mitochondrial stress, reducing ROS accumulation, preserving mitochondrial function, and extending lifespan. These findings reveal a novel anti‐aging mechanism of Vitamin K2 through mitochondrial protection and stress resistance enhancement.
Song‐Yu Guo, Yu‐Qi Li, Hua Piao, Wen‐Fei Zheng, Si‐Qi Li, Ze‐Yang Liu, Jun‐Ting Lv, Yue Kong, Qi‐Fa Li, Ying‐Zi Wang, Shu‐Zhuang Li, Chun‐Li Zhao, Shao Li   +12 more
wiley   +1 more source

Targeting the MAPK Pathway in Cancer. [PDF]

Int J Mol Sci
Kadasah SF.
europepmc   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Attack of the kinases: JNK signaling in metabolism. [PDF]

Am J Physiol Regul Integr Comp Physiol
Fernández-González I, Vattathara JJ, Davis RJ, Sabio G, López M.   +4 more
europepmc   +1 more source

Mitogen-activated protein kinase phosphatase-2 deletion impairs synaptic plasticity and hippocampal-dependent memory [PDF]

, 2015
Ungless, MA
core   +1 more source

Integrating Flow Cytometry in the Diagnostic Work of HIV‐Associated Hodgkin's Lymphomas

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Hodgkin lymphoma (HL) is prevalent worldwide and typically presents symptoms like sudden pain, swelling, and weight loss. Classical HL (cHL) is largely treatable with modern risk‐adapted and response‐based therapy. cHL represents one of the most common malignancies occurring during the course of evolution in patients living with HIV.
Maria Santa, Diana Cenariu, Adrian‐Bogdan Tigu, Marc Damian, Patricia Rantshabeng, Tendani Gaolathe, Andrew K. Ndlovu, Khalid Abdelrahman, Madalina Nistor, David Kegyes, Diana Gulei, Cristian Jinca, Anamaria Bancos, Ioana Rus, Horia Bumbea, Victor Tomacinschii, Sanda Buruiana, Rand Bilal, Cristina Selicean, Mihnea Zdrenghea, Bogdan Fetica, Cristina Stefan, Jonathan Fromm, Ciprian Tomuleasa   +23 more
wiley   +1 more source

Dissecting stress-activated protein kinase (SAPK)-signaling pathways using multiplex gene knockout HeLa cells. [PDF]

J Biol Chem
Ito C, Yamamoto M, Yokota N, Nakamura N, Shiomi M, Kizu M, Ichinose M, Fujii S, Fujii T, Fukunaga R.   +9 more
europepmc   +1 more source