Regulation of Cell Proliferation and Migration by Extracellular Phosphatidic Acid. [PDF]
Gomez-Larrauri A +4 more
europepmc +1 more source
Resveratrol for Cancer Radio‐Sensitization: Ready for Prime Time or Future Perspective
Resveratrol exerts antioxidant and anti‐inflammatory effects by reducing reactive oxygen species and suppressing NF‐κB and JAK/STAT signaling pathways. It modulates metabolic signaling through AMPK‐dependent inhibition of mTOR, influencing cell survival and inflammatory responses.
Maryam Fallah +7 more
wiley +1 more source
The dual-specificity phosphatase JSP1 regulates neutrophil adhesion via integrin-SRC signaling in vascular inflammation. [PDF]
Li L, Tonks NK.
europepmc +1 more source
Thymol is a natural monoterpene with antimicrobial, antioxidant, anti‐inflammatory, and anticancer activities relevant to food and biomedical applications. Its poor solubility and instability can be improved through nanodelivery systems. Thymol also supports sustainable food preservation and active packaging, although further clinical validation and ...
Farhang Hameed Awlqadr +8 more
wiley +1 more source
Mechanism of action of cisplatin on Na+/K+ ATPase of Caco-2 colon cells in vitro. [PDF]
Mourad R, Hodeify R, Kreydiyyeh S.
europepmc +1 more source
LZ‐8 reduced IL‐6 and COX‐2 in LPS‐stimulated macrophages, partly by inhibiting MyD88‐mediated JNK‐MAPK signaling. LZ‐8 reduced inflammation and swelling in the ankle and palm of the feet in the animal model. High‐dose LZ‐8 reduced synovial hyperplasia, and all doses protected articular cartilage.
Shao‐Wen Hung +3 more
wiley +1 more source
Narciclasine triggers apoptosis in osteosarcoma cells via JNK-mediated extrinsic and intrinsic pathways. [PDF]
Yang JS +6 more
europepmc +1 more source
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley +1 more source
Saffron and <i>Calculus bovis</i> combination exerts anti-hepatic fibrotic effect in liver fibrosis rats <i>via</i> the mitogen-activated protein kinases pathway. [PDF]
Sun SN +9 more
europepmc +1 more source
Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies
The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He +9 more
wiley +1 more source

