Results 291 to 300 of about 79,828 (321)
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European Journal of Biochemistry, 1999
Ultraviolet A (UVA; 320–400 nm) radiation in human skin fibroblasts induces a pattern of mitogen‐activated protein kinase (MAPK) activation consisting of a rapid and transient induction of p38 and c‐Jun‐N‐terminal kinase (JNK) activity but not extracellular signal‐regulated kinases (ERK).
Helmut Sies +5 more
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Ultraviolet A (UVA; 320–400 nm) radiation in human skin fibroblasts induces a pattern of mitogen‐activated protein kinase (MAPK) activation consisting of a rapid and transient induction of p38 and c‐Jun‐N‐terminal kinase (JNK) activity but not extracellular signal‐regulated kinases (ERK).
Helmut Sies +5 more
openaire +3 more sources
Journal of Food Science, 2016
AbstractGINST is a hydrolyzed ginseng extract produced by an in vitro process that imitates the metabolic function of bacteria in the human digestive track and has approved by the Ministry of Food and Drug Safety of Korea for the management of postprandial hyperglycemia.
Joon-Seung Han +2 more
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AbstractGINST is a hydrolyzed ginseng extract produced by an in vitro process that imitates the metabolic function of bacteria in the human digestive track and has approved by the Ministry of Food and Drug Safety of Korea for the management of postprandial hyperglycemia.
Joon-Seung Han +2 more
openaire +3 more sources
Atherosclerosis, 2010
Recent studies have demonstrated that palmitic acid (PA) could regulate endothelial progenitor cells (EPCs) function (migration, proliferation, survival and angiogenesis) via various signal pathways, but the effect of PA on EPCs apoptosis and associated mechanisms are still elusive.The human EPCs were obtained by Ficoll density gradient centrifugation ...
Qijun Jiang +10 more
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Recent studies have demonstrated that palmitic acid (PA) could regulate endothelial progenitor cells (EPCs) function (migration, proliferation, survival and angiogenesis) via various signal pathways, but the effect of PA on EPCs apoptosis and associated mechanisms are still elusive.The human EPCs were obtained by Ficoll density gradient centrifugation ...
Qijun Jiang +10 more
openaire +3 more sources
Behavioural Brain Research, 2013
Opioids have been widely used in clinical practice as potent pain relievers for centuries. However, opioids have many deleterious effects. It has been reported that opioid increases tau protein phosphorylation. Hyperphosphorylation of tau is also a pathological feature of Alzheimer's disease and other chronic neurodegenerative disorders.
Minghui Cao +6 more
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Opioids have been widely used in clinical practice as potent pain relievers for centuries. However, opioids have many deleterious effects. It has been reported that opioid increases tau protein phosphorylation. Hyperphosphorylation of tau is also a pathological feature of Alzheimer's disease and other chronic neurodegenerative disorders.
Minghui Cao +6 more
openaire +3 more sources
Cellular Signalling, 2001
We have investigated the termination of agonist-stimulated mitogen-activated protein (MAP) kinase activity in EAhy926 cells by MAP kinase phosphatase-2 (MKP-2). In cells expressing either wild-type (WT) or catalytically inactive (CI)-MKP-2, there was no significant differences in TNFalpha-stimulated JNK or p38 MAP kinase activity, however hydrogen ...
Robinson, C., Sloss, C.M., Plevin, R.J.
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We have investigated the termination of agonist-stimulated mitogen-activated protein (MAP) kinase activity in EAhy926 cells by MAP kinase phosphatase-2 (MKP-2). In cells expressing either wild-type (WT) or catalytically inactive (CI)-MKP-2, there was no significant differences in TNFalpha-stimulated JNK or p38 MAP kinase activity, however hydrogen ...
Robinson, C., Sloss, C.M., Plevin, R.J.
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Assays for JNK and p38 Mitogen-Activated Protein Kinases
2000Michael Karin, Tatsuhiko Sudo
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2008
Previous studies demonstrated the ability of Glucosamine (GlcN) to inhibit mRNA transcription level of Interleukin-1β (IL-1β)- stimulated genes. These genes are under the control of two transcription factors Activator Protein (AP)-1 and NF-kB. The aim of this study was to determine the effects of GlcN on mitogen-activated protein (MAP) kinase ...
SCOTTO D'ABUSCO, ANNA +5 more
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Previous studies demonstrated the ability of Glucosamine (GlcN) to inhibit mRNA transcription level of Interleukin-1β (IL-1β)- stimulated genes. These genes are under the control of two transcription factors Activator Protein (AP)-1 and NF-kB. The aim of this study was to determine the effects of GlcN on mitogen-activated protein (MAP) kinase ...
SCOTTO D'ABUSCO, ANNA +5 more
openaire +2 more sources
Beyond PI3Ks: targeting phosphoinositide kinases in disease
Nature Reviews Drug Discovery, 2023Joanna Triscott +2 more
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