Results 91 to 100 of about 12,814,396 (386)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

PENGARUH LOCUS OF CONTROL DAN PERILAKU KEPEMIMPINAN SITUASIONAL TERHADAP PRESTASI KERJA AUDITOR DENGAN KEPUASAN KERJA SEBAGAI VARIABEL INTERVENING

open access: yesEkuitas: Jurnal Ekonomi dan Keuangan, 2018
This study aimed to prove the impact locus of control and situational leadership behavior to auditor job performance through job satisfaction. This study uses a quantitative approach that focused on testing the hypothesis. Independent variables are locus
Dian Agustia
doaj   +1 more source

The factor analysis of organizational commitment, job satisfaction and performance among lecturers in Batam [PDF]

open access: yes, 2019
This article intended to determine the important elements in commitment, satisfaction and job performance of university lecturers. This study involved 179 respondents from 3 universities located in Batam, Indonesia.
Hazriyanto, Hazriyanto   +1 more
core   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Aging, Job Satisfaction, and Job Performance [PDF]

open access: yes, 1990
The national trend to earlier retirement is surprising in light of conventional wisdom holding that older workers are healthy, satisfied and productive employees -- sometimes even more so than their younger counterparts.
Levine, Phillip B.   +2 more
core   +1 more source

The Impact of Organizational Commitment on Job Performance

open access: yesInternational journal of economics and business administration, 2019
Purpose: This research discusses the direct effect of multicultural competencies, organizational fairness and organizational commitment on job performance. The primary data was collected using explanatory survey.
Suharto, Suyanto, Nedi Hendri
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri   +2 more
wiley   +1 more source

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