Results 31 to 40 of about 5,814 (145)

New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab

Frontiers in Neurology, 2020
Overview: We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis patients treated with natalizumab in 36 University Hospitals in Europe.
Inmaculada Toboso, Amalia Tejeda-Velarde, Roberto Alvarez-Lafuente, Rafael Arroyo, Harald Hegen, Florian Deisenhammer, Susana Sainz de la Maza, José C. Alvarez-Cermeño, Guillermo Izquierdo, Dolores Paramo, Pedro Oliva, Bonaventura Casanova, Eduardo Agüera-Morales, Diego Franciotta, Matteo Gastaldi, Oscar Fernández, Patricia Urbaneja, José M. Garcia-Dominguez, Fernando Romero, Alicia Laroni, Antonio Uccelli, Angel Perez-Sempere, Albert Saiz, Yolanda Blanco, Daniela Galimberti, Elio Scarpini, Carmen Espejo, Xavier Montalban, Ludwig Rasche, Friedemann Paul, Friedemann Paul, Inés González, Elena Álvarez, Cristina Ramo, Ana B. Caminero, Yolanda Aladro, Carmen Calles, Pablo Eguía, Antonio Belenguer-Benavides, Lluis Ramió-Torrentà, Ester Quintana, José E. Martínez-Rodríguez, Agustín Oterino, Carlos López de Silanes, Luis I. Casanova, Lamberto Landete, Jette Frederiksen, Gabriel Bsteh, Patricia Mulero, Manuel Comabella, Miguel A. Hernández, Mercedes Espiño, José M. Prieto, Domingo Pérez, María Otano, Francisco Padilla, Juan A. García-Merino, Laura Navarro, Alfonso Muriel, Lucienne Costa Frossard, Luisa M. Villar   +60 more
doaj   +1 more source

Hepatitis B virus-induced CD4 lymphocytopenia: A rare cause of progressive multifocal leukoencephalopathy

Asian Journal of Medical Sciences, 2022
Progressive multifocal leukoencephalopathy (PML) is a rare subacute-onset fatal demyelinating disease of the central nervous system caused by the John Cunningham (JC) virus.
Amar Kumar Mishra , Sanjay Kumar , Niraja Agasti , Gautam Guha , Saikat Ghosh , Bijendra Mohanty , Pideno S Ngullie , Joydeep Mukherjee   +7 more
doaj   +1 more source

Smoldering myeloma presenting as progressive multifocal leukoencephalopathy: a case report

Journal of Medical Case Reports, 2012
Introduction Progressive multifocal leukoencephalopathy is an opportunistic infection occurring in patients with severe cellular immunodeficiency. This case highlights the role of cellular immunodeficiency in the reactivation of John Cunningham virus in ...
Troppmann Martina, Büttner Roland, Böwer Michael, Salzberger Bernd   +3 more
doaj   +1 more source

Progressive Multifocal Leukoencephalopathy and Immune Reconstitution Inflammatory Syndrome after Discontinuation of Fingolimod

Case Reports in Neurology, 2022
Progressive multifocal leukoencephalopathy (PML) is a rare complication of immunosuppressive treatment in MS patients. Immune reconstitution inflammatory syndrome (IRIS) appears after the withdrawal of certain drugs such as natalizumab (NTZ) or ...
Raquel Piñar Morales, María Carrasco Garcia, Luis Gutierrez-Rojas, Francisco Javier Barrero Hernández   +3 more
doaj   +1 more source

Viruria of Human BK Virus and John Cunningham Virus among Renal Transplant Recipients and Healthy Control in Southeast of Caspian Sea [PDF]

Intervirology, 2021
<b><i>Background:</i></b> Members of the Polyomaviridae family, BK virus (BKV), and John Cunningham virus (JCV) are linked to polyomavirus-associated nephropathy-associated transplant rejection in immunodeficient patients. <b><i>Objective:</i></b> The aim of the study was to evaluate the prevalence of BKV
Fereshteh Safaei, Alireza Mohebbi, Mina Hassanpour, Hadi Razavi Nikoo, Alijan Tabarraei   +4 more
openaire   +2 more sources

Understanding Progressive Multifocal Leukoencephalopathy Risk in Multiple Sclerosis Patients Treated with Immunomodulatory Therapies: A Bird’s Eye View

Frontiers in Immunology, 2018
The increased use of newer potent immunomodulatory therapies for multiple sclerosis (MS), including natalizumab, fingolimod, and dimethyl fumarate, has expanded the patient population at risk for developing progressive multifocal leukoencephalopathy (PML)
Elizabeth A. Mills, Yang Mao-Draayer, Yang Mao-Draayer   +2 more
doaj   +1 more source

Late Occurrence of PML in a Patient Treated for Lymphoma with Immunomodulatory Chemotherapies, Bendamustine, Rituximab, and Ibritumomab Tiuxetan

Case Reports in Neurological Medicine, 2015
PML caused by John Cunningham (JC) virus is a rare but an increasingly recognized entity. With the advent of newer immunomodulatory therapies with monoclonal antibodies, there is an increasing incidence of PML.
Michael A. Lane, Vijay Renga, Andrew R. Pachner, Jeffrey A. Cohen   +3 more
doaj   +1 more source

Isolated posterior fossa involvement of progressive multifocal leucoencephalopathy in HIV: A case series with review of the literature

South African Journal of Radiology, 2017
Progressive multifocal leucoencephalopathy (PML) is a progressive demyelinating condition resulting from infection with the John Cunningham virus and precipitated by immunocompromised states.
Adziambei Mudau, Farhana E. Suleman, Clara M. Schutte, Zarina I. Lockhat   +3 more
doaj   +1 more source

Feathers and flu: identifying data gaps in avian influenza host dynamics to prioritize wildlife conservation Plumas y gripe: identificación de datos faltantes en la dinámica de hospedadores de la influenza aviar para priorizar la conservación de la vida silvestre

Wildlife Monographs, EarlyView.
We describe the host response continuum for highly pathogenic avian influenza viruses (HPAIV), including the continuum of host responses to HPAIV infection and exposure based on the primary axis of host competence, ability to infect other hosts, and host vulnerability.
Johanna A. Harvey, Matthew Gonnerman, Shenglai Yin, Cody M. Kent, Joshua Cullen, Jeffery D. Sullivan, Jonathan B. Dain, Nichola J. Hill, Diann J. Prosser, Jennifer M. Mullinax   +9 more
wiley   +1 more source

Improving the use of expert opinion in disease risk analysis for conservation translocations

Conservation Biology, EarlyView.
Abstract Conservation translocations are subject to considerable uncertainty and risk, of which disease is one of the most recognized. To address disease risks, several protocols for qualitative disease risk analysis (qDRA) exist and are used for responsible conservation translocation planning.
John G. Ewen, Stefano Canessa, Caitlin E. Andrews, Katie M. Beckmann, Irene Bueno, Deidre K. Fontenot, Caio Kenup, Suzanne Medina, Axel Moehrenschlager, Francesco Origgi, Bruce Rideout, Anthony W. Sainsbury, Thierry M. Work, Claudia Carraro   +13 more
wiley   +1 more source