Results 51 to 60 of about 94,991 (291)

Research on Dynamic Wear of Revolution Joint with Clearance for Mechanical System

open access: yes, 2011
In order to study the dynamic wear of revolution joint with clearance in mechanical system, the dynamic model of mechanical system with joint clearance is presented. The clearance model is established based on clearance vector model.
Yang Zhao, Zheng Feng Bai
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Nonlinear Characteristic of Spherical Joints with Clearance

open access: yesJournal of Aerospace Technology and Management, 2015
Joints in deployable structures can degrade the stiffness and the stability of spacecraft. In this study, the nonlinear stiffness of spherical joints is investigated. The traditional contact model of spherical joints based on non-conforming contact assumption is presented.
Jing, Zhang   +3 more
openaire   +5 more sources

含运动副间隙的双万向节系统动力学研究

open access: yesJixie chuandong, 2012
The solid model of the system of double cardan joint is built through Pro/Engineer,then it is imported into ADAMS to take the dynamic simulation analysis.For the model which does not contain joint clearance,the proper restrain is added according to ...
张辉, 葛文杰, 宁方立, 赵炜
doaj  

Dynamic Modeling and Simulation of a Rotating Single Link Flexible Robotic Manipulator Subject to Quick Stops

open access: yes, 2014
Single link robotic manipulators are extensively used in industry and research operations. The main design requirement of such manipulators is to minimize link dynamic deflection and its active end vibrations, and obtain high position accuracy during its
Noroozi, Siamak, Dupac, Mihai
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

POLYCENTRIC EXOPROSTHETIC KNEE JOINTS – EXTENT OF SHORTENING DURING SWING PHASE

open access: yesCanadian Prosthetics & Orthotics Journal, 2020
BACKGROUND: An often assumed advantage of polycentric knee joints compared to monocentric ones is the improved ground clearance during swing phase due to the geometric shortening of the lower leg segment (LLS).
Thomas Maximilian Köhler   +2 more
doaj   +1 more source

Effect of joint clearance on fatigue strength of brazed joint.

open access: yesQUARTERLY JOURNAL OF THE JAPAN WELDING SOCIETY, 1989
The effects of joint clearance on fatigue crack initiation life and crack growth rate of brazed joint were investigated.Tes tspecimens used were butt joint of carbon stcel and stainless steel brazed with pure copper with/without an artificial defect in joint.It was inferred from the fatigue test results that fatigue life of joint depend not on crack ...
openaire   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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