Results 131 to 140 of about 13,555 (204)

JQ1 Downregulates IL-20RA Expression in Triple Negative Breast Cancer Cells In Vitro and In Vivo. [PDF]

Int J Mol Sci
Maggisano V, Panza S, Verrienti A, Lombardo GE, Catalano S, Bulotta S.   +5 more
europepmc   +1 more source

BRD2 upregulation as a pan-cancer adaptive resistance mechanism to BET inhibition. [PDF]

Cell Mol Biol Lett
Archasappawat S, Jacques J, Lee E, Hwang CI.   +3 more
europepmc   +1 more source

Direct toll-like receptor 4 inhibition in Alzheimer's disease models: a focused scoping review of inflammatory, amyloid-handling, and functional outcomes. [PDF]

Front Aging Neurosci
Ren X, Jin X, Li L, Li F.
europepmc   +1 more source

scTumorDrug: predicting cell-type-specific drug responses for heterogeneous tumors. [PDF]

Brief Bioinform
Zhang Q, Zhang Q, Guo C, Peng C.
europepmc   +1 more source

Resistance to the KRASG12D Inhibitor MRTX1133 Is Associated with Increased Sensitivity to BET Inhibition. [PDF]

Mol Cancer Ther
Principe DR, Becker JH, Metropulos AE, Marinelarena AM, Pham TD, Aissa AF, Munshi HG.   +6 more
europepmc   +1 more source

Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation. [PDF]

PLoS Pathog
Chen J, Fan J, Qin M, Lin Z, Mu S, Dai L, Qin Z.   +6 more
europepmc   +1 more source

Unc-51 like kinase 3 (ULK3) contributes to autophagy and cell survival in multiple myeloma. [PDF]

Nat Commun
Tauro M, Li T, Sudalagunta PR, Meads M, Canevarolo RR, Nerlakanti N, Alugubelli RR, Lawrence HR, Tantak MP, Gunawan S, Ayaz M, Nareddy P, Yun SY, Shay G, Yang Y, Tran TH, Atkins R, Locke FL, Bishop RT, Nasr MM, Lawrence NJ, Schönbrunn E, Cleveland JL, Silva AS, Shain KH, Lynch CC.   +25 more
europepmc   +1 more source

Single-Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re-Sensitizer Drugs in Triple-Negative Breast Cancer. [PDF]

Adv Sci (Weinh)
Liu H, Yuan M, Shang Y, Chen J, Hou F, Wang L, Jiang W.   +6 more
europepmc   +1 more source

Cell painting and thermal proteome profiling for inference of drug targets and mechanism of action. [PDF]

Mol Syst Biol
Johansson C, Johansson M, Kasi PB, Larsson M, Jakobsson PJ, Göransson U, Carreras Puigvert J, Spjuth O, Jansson ET.   +8 more
europepmc   +1 more source

Enzyme-Induced Supramolecular Proteolysis-Targeting Chimeras Enable Tumor-Targeted Protein Degradation. [PDF]

JACS Au
Liang C, Ma X, Chen X, Dai C, Sun X, Li J, Dong R, Dong P, Wang M.   +8 more
europepmc   +1 more source