Results 141 to 150 of about 14,237 (205)

Parasite-specific essential bromodomain protein TgBDP4 is a key epigenetic reader and a potential drug target for the parasite Toxoplasma gondii. [PDF]

J Biol Chem
Gurupwar R, Khandavalli CR, Deshmukh AS.
europepmc   +1 more source

BRD4 inhibition suppresses histone H4 UFMylation to increase ferroptosis sensitivity through TXNIP. [PDF]

Cell Death Dis
Yang Z, Wang B, Guo B, Sun S, Li Y, Lu J, Cao X, Wang H, Wang X, Guo Y, Wu T.   +10 more
europepmc   +1 more source

Bioorthogonal Sonodynamic Plug-and-Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation. [PDF]

Adv Sci (Weinh)
Bao Y, Zhu Y, Wei X, Fang Y, Zhu J, Gao F, Dong G, He S, Sheng C.   +8 more
europepmc   +1 more source

BET Bromodomain Inhibition Reverses CDK4/6 Inhibitor Resistance in Estrogen Receptor-Positive Breast Cancer via Induction of miR-34a-5p. [PDF]

Clin Cancer Res
Liu R, Wang X, Branigan TB, Griffin D, McSweeney C, Hao J, Pantelidou C, Herbert ZT, Jadhav H, Shapiro GI.   +9 more
europepmc   +1 more source

Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer. [PDF]

Oncogene
Spellecy O, Qadir J, Han R, Zhu K, Xu B, Zhang Y, Aryal I, Lin RL, Lin AH, Faisal ASM, Napier D, Piecoro D, Scott T, Lin P, Chen L, Brewer LD, Wang C, Kyprianou N, Guo Z, Guo R, Thibault O, Yang BB, Yang XH.   +22 more
europepmc   +1 more source

BRD4 inhibitor JQ1 inhibits viability of hepatocellular carcinoma cells

World Chinese Journal of Digestology, 2016
openaire   +1 more source

Combinational BET and mTOR inhibition unveils EGR1 as acute myeloid leukemia prognostic biomarker. [PDF]

Sci Rep
Latancia MT, Silva WFD, Bragança-Jardim E, Terra FF, Asprino PF, Pereira WO, Buzatto VC, Galante PA, Inoue LT, Fonseca AR, Kimmemgs TN, Arrais-Rodrigues C, Rocha V, Novis Y, Camara NOS, Lepique AP, Reis LFL, Amano MT.   +17 more
europepmc   +1 more source

A new 4-atom linker enables PROTAC development and imaging. [PDF]

RSC Chem Biol
Letsios S, Carrasco G, Lee M, Wagiet M, Madureira M, Samways M, Khan Z, Brunton VG, Grubisha O, Hulme AN.   +9 more
europepmc   +1 more source

Decoding Bromodomain and Extra-Terminal Domain Protein-Mediated Epigenetic Mechanisms in Human Uterine Fibroids. [PDF]

Int J Mol Sci
Yang Q, Vafaei S, Falahati A, Khosh A, Omran MM, Bai T, Bariani MV, Ali M, Boyer TG, Al-Hendy A.   +9 more
europepmc   +1 more source