Results 121 to 130 of about 14,237 (205)

SP048THE BET BROMODOMAIN INHIBITOR JQ1 DIMINISHED RENAL FIBROSIS [PDF]

Nephrology Dialysis Transplantation, 2016
Sandra Rayego-Mateos, José Luis Morgado-Pascual, Beatriz Suarez-Alvarez Suarez-Alvarez, Macarena Orejudo, Raúl R. Rodrigues-Díez, Laura Marquez-Exposito, Jesús Egido, Alberto Ortiz, Carlos Lopez-Larrea, Marta Ruiz-Ortega   +9 more
openaire   +1 more source

Resistance to the KRASG12D Inhibitor MRTX1133 Is Associated with Increased Sensitivity to BET Inhibition. [PDF]

Mol Cancer Ther
Principe DR, Becker JH, Metropulos AE, Marinelarena AM, Pham TD, Aissa AF, Munshi HG.   +6 more
europepmc   +1 more source

scTumorDrug: predicting cell-type-specific drug responses for heterogeneous tumors. [PDF]

Brief Bioinform
Zhang Q, Zhang Q, Guo C, Peng C.
europepmc   +1 more source

Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation. [PDF]

PLoS Pathog
Chen J, Fan J, Qin M, Lin Z, Mu S, Dai L, Qin Z.   +6 more
europepmc   +1 more source

Single-Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re-Sensitizer Drugs in Triple-Negative Breast Cancer. [PDF]

Adv Sci (Weinh)
Liu H, Yuan M, Shang Y, Chen J, Hou F, Wang L, Jiang W.   +6 more
europepmc   +1 more source

Enzyme-Induced Supramolecular Proteolysis-Targeting Chimeras Enable Tumor-Targeted Protein Degradation. [PDF]

JACS Au
Liang C, Ma X, Chen X, Dai C, Sun X, Li J, Dong R, Dong P, Wang M.   +8 more
europepmc   +1 more source

Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1. [PDF]

Proc Natl Acad Sci U S A
Tanis S, Simon LE, Alexander AK, Horan TS, Carro MLM, Bonnett SJ, Xie A, Ben-Shlomo R, Owens CE, Danko CG, Lujic J, Cohen PE.   +11 more
europepmc   +1 more source

BRD4 Inhibition alleviates sepsis-associated acute kidney injury via suppression of NOX4-mediated oxidative stress and inflammation. [PDF]

Cell Death Discov
Jia J, Ji K, Zhou Y, Huang Y, Li A, Ye F, Huang W, Chen F, Lu G.   +8 more
europepmc   +1 more source

NHWD-870, a Potent BET Inhibitor, Ameliorated Endotoxemia-Induced Hepatic Inflammation via Suppression of BRD4-STAT1 Signaling and Macrophage M1 Polarization. [PDF]

J Inflamm Res
Zhou N, Tan B, Jiang Y, Wang H, Peng W, Yin M, Fu L, Peng S.   +7 more
europepmc   +1 more source

BET inhibition disrupts the FOXM1-MYC axis to induce BRCAness and enhance PARP inhibitor response. [PDF]

NPJ Precis Oncol
Fang P, Saunders A, Minn K, Chua KJ, Brooks RA, Bakke D, Leiserowitz GS, Johnson N, Wang S, Chien J.   +9 more
europepmc   +1 more source