fENko-Kae01 is a flagellum-specific jumbo phage infecting Klebsiella aerogenes [PDF]
BMC MicrobiologyBackground Klebsiella aerogenes is an opportunistic pathogen that causes a wide variety of infections. Due to the rising problem of antibiotic resistance, novel antibiotics and strategies to combat bacterial infections are needed.
Kira Ranta +2 more
doaj +6 more sources
Interactions between Jumbo Phage SA1 and Staphylococcus: A Global Transcriptomic Analysis [PDF]
Microorganisms, 2022 Staphylococcus aureus (S. aureus) is an important zoonotic pathogen that poses a serious health concern to humans and cattle worldwide. Although it has been proven that lytic phages may successfully kill S.
Bingyan Zhang +4 more
doaj +5 more sources
Characterization and application of a lytic jumbo phage ZPAH34 against multidrug-resistant Aeromonas hydrophila [PDF]
Frontiers in Microbiology, 2023 Aeromonas hydrophila is an emerging foodborne pathogen causing human gastroenteritis. Aeromonas species isolated from food such as seafood presented multidrug-resistance (MDR), raising serious concerns regarding food safety and public health.
Yuting Hou +8 more
doaj +3 more sources
Characterization and genomic study of EJP2, a novel jumbo phage targeting antimicrobial resistant Escherichia coli [PDF]
Frontiers in Microbiology, 2023 The emergence of antimicrobial resistance (AMR) Escherichia coli has noticeably increased in recent years worldwide and causes serious public health concerns.
Dohyeong Jo +4 more
doaj +3 more sources
The Dynamics of Synthesis and Localization of Jumbo Phage RNA Polymerases inside Infected Cells [PDF]
Viruses, 2023 A nucleus-like structure composed of phage-encoded proteins and containing replicating viral DNA is formed in Pseudomonas aeruginosa cells infected by jumbo bacteriophage phiKZ. The PhiKZ genes are transcribed independently from host RNA polymerase (RNAP)
Daria Antonova +11 more
doaj +3 more sources
Bacterial cytological profiling reveals interactions between jumbo phage φKZ infection and cell wall active antibiotics in Pseudomonas aeruginosa. [PDF]
PLoS ONE, 2023 The emergence of antibiotic resistance in bacteria has led to the investigation of alternative treatments, such as phage therapy. In this study, we examined the interactions between the nucleus-forming jumbo phage ФKZ and antibiotic treatment against ...
Hannah Tsunemoto +4 more
doaj +3 more sources
Characterization of a novel Jumbo phage JP4 with potential to control pathogenic Escherichia coli [PDF]
Virology JournalBackground Amidst rising antimicrobial resistance, bacteriophage (phage) therapy has re-emerged as a pivotal weapon against multidrug-resistant pathogens. Jumbo phages, distinguished by large genomes, show particular therapeutic promise.
Kexin Zhang +13 more
doaj +3 more sources
Isolation and characterization of vB_XciM_LucasX, a new jumbo phage that infects Xanthomonas citri and Xanthomonas fuscans. [PDF]
PLoS ONE, 2022 Citrus canker is one of the main bacterial diseases that affect citrus crops and is caused by Xanthomonas citri which affects all citrus species worldwide.
Vinícius Marquioni +7 more
doaj +4 more sources
Isolation and characterization of fMGyn-Pae01, a phiKZ-like jumbo phage infecting Pseudomonas aeruginosa [PDF]
Virology JournalBackground Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide variety of infections, and belongs to the group of ESKAPE pathogens that are the leading cause of healthcare-associated infections and have high level of antibiotic ...
Kira Ranta +2 more
doaj +3 more sources
Isolation and Characterization of a Novel Jumbo Phage from Leaf Litter Compost and Its Suppressive Effect on Rice Seedling Rot Diseases [PDF]
Viruses, 2021 Jumbo phages have DNA genomes larger than 200 kbp in large virions composed of an icosahedral head, tail, and other adsorption structures, and they are known to be abundant biological substances in nature.
Ryota Sasaki +5 more
doaj +3 more sources