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Current Biology, 2023
In this Quick guide, Harding et al. introduce jumbo phages - the overlooked giants of the phage universe.
Kate R, Harding +2 more
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In this Quick guide, Harding et al. introduce jumbo phages - the overlooked giants of the phage universe.
Kate R, Harding +2 more
openaire +2 more sources
Investigating the early stages of infection of nucleus-forming jumbo phage.
Biophysical Journal, 2023Zaida K. Rodriguez +9 more
semanticscholar +2 more sources
Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection
Molecular Cell, 2022SUMMARYBacteria have diverse defences against phages. In response, jumbo phages evade multiple DNA-targeting defences by protecting their DNA inside a nucleus-like structure. We previously demonstrated that RNA-targeting type III CRISPR–Cas systems provide jumbo phage immunity by recognising viral mRNA exported from the nucleus for translation.
David Mayo-Muñoz +9 more
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A novel environmental pseudomonas jumbo phage PseuM_296: genome analysis and putative taxonomy
Четырнадцатая международная мультиконференция : Тез. докл.semanticscholar +2 more sources
Here we collected 59,652,008 putative viral genomes spanning seven different habitats by using 38 public metagenome datasets, an integrated public viral genome database (IGNR), and a pig gut viral genome database (PGV). A total of 10,754 megaphage genomes were obtained with genome sizes from 200 to 831 kb.
Wei, Chao, Huang, Lusheng
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Wei, Chao, Huang, Lusheng
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A novel jumbo Tenacibaculum maritimum lytic phage with head-fiber-like appendages
Archives of Virology, 2019A novel jumbo bacteriophage (myovirus) is described. The lytic phage of Tenacibaculum maritimum, which is the etiological agent of tenacibaculosis in a variety of farmed marine fish worldwide, was plaque-isolated from seawater around a fish aquaculture field in Japan. The phage had an isometric head 110-120 nm in diameter, from which several 50- to 100-
Yasuhiko Kawato +9 more
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A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli.
2022Nucleus-forming jumbo phages establish an intricate subcellular organization, enclosing phage genomes within a proteinaceous shell called the phage nucleus. During infection in Pseudomonas, some jumbo phages assemble a bipolar spindle of tubulin-like PhuZ filaments that positions the phage nucleus at midcell and drives its intracellular rotation.
Birkholz, Erica A +8 more
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Interactions between bacterial and phage communities in natural environments
Nature Reviews Microbiology, 2021Anne Chevallereau +2 more
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