Results 61 to 70 of about 98,997 (145)
Viruses, 2021 Jumbo phages have attracted much attention by virtue of their extraordinary genome size and unusual aspects of biology. By performing a comparative genomics analysis of 224 jumbo phages, we suggest an objective inclusion criterion based on genome size ...
Lakshminarayan M. Iyer +4 more
doaj +1 more source
Selective transport of fluorescent proteins into the phage nucleus
PLoS ONE, 2021 Upon infection of Pseudomonas cells, jumbo phages 201Φ2–1, ΦPA3, and ΦKZ assemble a phage nucleus. Viral DNA is enclosed within the phage-encoded proteinaceous shell along with proteins associated with DNA replication, recombination and transcription ...
Katrina T. Nguyen +8 more
doaj +2 more sources
Subcellular organization of viral particles during maturation of nucleus-forming jumbo phage
bioRxiv, 2021 Many eukaryotic viruses assemble mature particles within distinct subcellular compartments, but bacteriophages were long assumed to assemble randomly throughout the host cell cytoplasm.
Vorrapon Chaikeeratisak +8 more
semanticscholar +1 more source
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice
Nature Communications, 2023 To protect from host attack, numerous jumbo bacteriophages establish a micron-scale, protein-based structure to enclose their replicating DNA. Using cryoEM, the authors show that the 2D crystal enclosing this so-called phage nucleus is an assembly of ...
Eliza S. Nieweglowska +9 more
doaj +1 more source
Pathogens, 2020 Vibrio harveyi is a Gram-negative marine bacterium that causes major disease outbreaks and economic losses in aquaculture. Phage therapy has been considered as a potential alternative to antibiotics however, candidate bacteriophages require comprehensive
Gerald N. Misol +2 more
doaj +1 more source
Microorganisms, 2023 Colibacillosis in chickens can cause the death of young stock, decrease weight gain and lead to significant economic losses. Currently, antibiotic therapy is the main method of treatment of infected animals, but unchecked use of antibiotics has led to ...
Pavel Alexyuk +5 more
doaj +1 more source
Microbiology SpectrumJumbo phages are characterized by their remarkably large-sized genome and unique life cycles. Jumbo phages belonging to Chimalliviridae family protect the replicating phage DNA from host immune systems like CRISPR-Cas and restriction-modification system ...
Sharayu Magar +3 more
doaj +1 more source
Differential Bacteriophage Efficacy in Controlling Salmonella in Cattle Hide and Soil Models
Frontiers in Microbiology, 2021 Asymptomatic Salmonella carriage in beef cattle is a food safety concern and the beef feedlot environment and cattle hides are reservoirs of this pathogen. Bacteriophages present an attractive non-antibiotic strategy for control of Salmonella in beef. In
Yicheng Xie +9 more
doaj +1 more source
iMetaOmics, EarlyView.Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo +9 more
wiley +1 more source
Characterization and genomic analysis of Sharanji: a jumbo bacteriophage of Escherichia coli
Virology JournalBackground Bacteriophages are the most genetically diverse biological entities in nature. Our current understanding of phage biology primarily stems from studies on a limited number of model bacteriophages.
Sharayu Magar +6 more
doaj +1 more source