Results 61 to 70 of about 871 (146)
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice
Nature Communications, 2023 To protect from host attack, numerous jumbo bacteriophages establish a micron-scale, protein-based structure to enclose their replicating DNA. Using cryoEM, the authors show that the 2D crystal enclosing this so-called phage nucleus is an assembly of ...
Eliza S. Nieweglowska +9 more
doaj +1 more source
Pathogens, 2020 Vibrio harveyi is a Gram-negative marine bacterium that causes major disease outbreaks and economic losses in aquaculture. Phage therapy has been considered as a potential alternative to antibiotics however, candidate bacteriophages require comprehensive
Gerald N. Misol +2 more
doaj +1 more source
The Biology of Nucleus-Forming Jumbo Phages
Annual Review of GeneticsNucleus-forming jumbo bacteriophages display a surprisingly intricate replication cycle inside of bacterial host cells, challenging the long-standing paradigm of prokaryotic simplicity. The phage nucleus encloses phage DNA in a protein shell, strictly uncouples transcription from translation, and facilitates selective protein import and messenger RNA ...
Birkholz, Erica A. +2 more
openaire +2 more sources
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury +3 more
wiley +1 more source
, 2023 Phage genomes (bins and unbinned contig) larger than 100kb.
Benjamin Minch (16495497)
core +1 more source
Characterization and genomic analysis of Sharanji: a jumbo bacteriophage of Escherichia coli
Virology JournalBackground Bacteriophages are the most genetically diverse biological entities in nature. Our current understanding of phage biology primarily stems from studies on a limited number of model bacteriophages.
Sharayu Magar +6 more
doaj +1 more source
Natural Sciences, Volume 6, Issue 3, July 2026.ABSTRACT Proposing the concept of a conservative revolutionary generally and using the examples of Gregor Mendel, Max Delbrück, and Eric Davidson, I fundamentally call into question Thomas Kuhn's ideas of scientific revolutions. I also highlight some problematic consequences of the increasing appreciation of Kuhn's work among scientists and show that ...
Ute Deichmann
wiley +1 more source
The human oral phageome is highly diverse and rich in jumbo phages [PDF]
, 2020 Abstract Until recently, the contribution of bacteriophages to the composition and function of the human microbiome has been largely overlooked. Recent developments in discovering novel bacteriophages from human metagenomes have been mostly focused on the gut.
Victoria R. Carr +5 more
openaire +1 more source
Microorganisms, 2023 Colibacillosis in chickens can cause the death of young stock, decrease weight gain and lead to significant economic losses. Currently, antibiotic therapy is the main method of treatment of infected animals, but unchecked use of antibiotics has led to ...
Pavel Alexyuk +5 more
doaj +1 more source
iNew Medicine, Volume 2, Issue 2, June 2026.This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source