Results 51 to 60 of about 99,420 (188)

Complete Genome Sequence of a Jumbo Bacteriophage, Escherichia Phage vB_EcoM_EC001

Microbiology Resource Announcements, 2022
Here, we report the genome sequence of a jumbo Escherichia phage vB_EcoM_EC001, a myovirus isolated from primary sludge using enterohemorrhagic Escherichia coli O157:H7. The genome is 240,200 bp long and has 270 predicted coding sequences, including a tryptophanyl tRNA gene.
Stevan Cucić, Andrew M. Kropinski, Janet Lin, Cezar M. Khursigara, Hany Anany   +4 more
openaire   +3 more sources

Multisubunit RNA Polymerases of Jumbo Bacteriophages

Viruses, 2020
Prokaryotic viruses with DNA genome longer than 200 kb are collectively referred to as “jumbo phages”. Some representatives of this phylogenetically diverse group encode two DNA-dependent RNA polymerases (RNAPs)—a virion RNAP and a non-virion RNAP.
Maria L. Sokolova, Inna Misovetc, Konstantin V. Severinov   +2 more
doaj   +1 more source

Characterization and Genomic Analysis of a Novel Jumbo Bacteriophage vB_StaM_SA1 Infecting Staphylococcus aureus With Two Lysins

Frontiers in Microbiology, 2022
The development of new antimicrobial agents is critically needed due to the alarming increase in antibiotic resistance in bacterial pathogens. Phages have been widely considered as effective alternatives to antibiotics.
Bingyan Zhang, Bingyan Zhang, Huzhi Sun, Feiyang Zhao, Qian Wang, Qiang Pan, Yigang Tong, Huiying Ren   +7 more
doaj   +1 more source

Defining the constituents and functions of a lipid-based jumbo phage compartment

bioRxiv
Viruses are vulnerable to cellular defenses at the start of the infection when a single copy genome has not yet initiated de novo viral protein synthesis. A family of jumbo phages related to phage ΦKZ, which infects Pseudomonas aeruginosa, uses a protein-
Deepto Mozumdar, A. Fossati, Erica Stevenson, J. Guan, Eliza S. Nieweglowska, Sanjana Rao, D. Agard, D. Swaney, Joseph Bondy-Denomy   +8 more
semanticscholar   +2 more sources

Characterization of Novel Erwinia amylovora Jumbo Bacteriophages from Eneladusvirus Genus

Viruses, 2020
Jumbo phages, which have a genome size of more than 200 kb, have recently been reported for the first time. However, limited information is available regarding their characteristics because few jumbo phages have been isolated.
Sang Guen Kim, Sung Bin Lee, Sib Sankar Giri, Hyoun Joong Kim, Sang Wha Kim, Jun Kwon, Jungkum Park, Eunjung Roh, Se Chang Park   +8 more
doaj   +1 more source

Things Are Getting Hairy: Enterobacteria Bacteriophage vB_PcaM_CBB [PDF]

, 2017
Enterobacteria phage vB_PcaM_CBB is a jumbo phage belonging to the family Myoviridae. It possesses highly atypical whisker-like structures along the length of its contractile tail. It has a broad host range with the capability of infecting species of the
Abbasifar, Ackermann, Ackermann, Bailey, Barry, Bell, Besemer, Brewer, Briers, Briers, Buttimer, Casjens, Comeau, Darrasse, De Boer, Delcher, Drulis-Kawa, Dwivedi, Edgell, Estrem, Finn, Fouts, Fraser, Geiduschek, Hatfull, Hendrix, Hendrix, Hertveldt, Hélias, Jones, Kanamaru, Kang, Keppel, Kim, Kumar, Käll, Laslett, Li, Lingohr, Lowe, Mazzocco, Mesyanzhinov, Mitchell, Naville, Nelson, Nikolaichik, Park, Petrov, Pickard, Rahman, Redzuan, Rocha, Sambrook, Sambrook, Sambrook, Samson, Schweiger, Sengupta, Serwer, Skurnik, Sullivan, Sullivan, Szewczyk, Söding, Tori, Tsones, Turner, Van den Bossche, Van Twest, Walldén, Wang, Whitman, Xu, Yuan, Zhong, Zhu, Zuker, Šimolūnas   +77 more
core   +5 more sources

Characterization and Genomic Analysis of PALS2, a Novel Staphylococcus Jumbo Bacteriophage

Frontiers in Microbiology, 2021
Staphylococcus aureus is an important human pathogen that can be frequently encountered in clinical and food-processing surroundings. Among the various countermeasures, bacteriophages have been considered to be promising alternatives to antibiotics.
Yoona Lee, Yoona Lee, Bokyung Son, Bokyung Son, Yoyeon Cha, Yoyeon Cha, Sangryeol Ryu, Sangryeol Ryu, Sangryeol Ryu, Sangryeol Ryu   +9 more
doaj   +1 more source

Modeling the architecture of depolymerase-containing receptor binding proteins in Klebsiella phages [PDF]

, 2019
Klebsiella pneumoniae carries a thick polysaccharide capsule. This highly variable chemical structure plays an important role in its virulence. Many Klebsiella bacteriophages recognize this capsule with a receptor binding protein (RBP) that contains a ...
Briers, Yves, Drulis-Kawa, Zuzanna, Leiman, Petr G, Łątka, Agnieszka   +3 more
core   +2 more sources

Clades of huge phages from across Earth's ecosystems. [PDF]

, 2020
Bacteriophages typically have small genomes1 and depend on their bacterial hosts for replication2. Here we sequenced DNA from diverse ecosystems and found hundreds of phage genomes with lengths of more than 200 kilobases (kb), including a genome of ...
Al-Shayeb, Basem, Amano, Yuki, Amundson, Ronald, Anantharaman, Karthik, Banfield, Jillian F, Borton, Mikayla A, Bouma-Gregson, Keith, Brooks, Brandon, Castelle, Cindy J, Cate, Jamie HD, Chen, Lin-Xing, Devoto, Audra, Doudna, Jennifer A, Farag, Ibrahim F, Finstad, Kari, Goltsman, Daniela SA, Harrison, Sue, He, Christine, Jaffe, Alexander L, Kantor, Rose, Keren, Ray, Lane, Katherine R, Lavy, Adi, Lehours, Anne-Catherine, Lei, Shufei, Li, Wen-Jun, Matheus-Carnevali, Paula, Morowitz, Michael, Munk, Patrick, Méheust, Raphaël, Nelson, Tara C, Olm, Matthew R, Power, Mary E, Probst, Alexander J, Relman, David A, Sachdeva, Rohan, Santini, Joanne M, Sharrar, Allison, Sun, Christine, Thomas, Alex, Tringe, Susannah G, Ward, Fred, Warren, Lesley, Wrighton, Kelly, Zhou, Jinglie   +44 more
core   +2 more sources

Diversity and function of phage encoded depolymerases [PDF]

, 2020
Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as structural components of the virion. These enzymes appear as tail spike proteins (TSPs).
Fieseler, Lars, Knecht, Leandra E., Veljkovic, Marjan   +2 more
core   +1 more source