Results 61 to 70 of about 585 (130)

Differential Bacteriophage Efficacy in Controlling Salmonella in Cattle Hide and Soil Models

Frontiers in Microbiology, 2021
Asymptomatic Salmonella carriage in beef cattle is a food safety concern and the beef feedlot environment and cattle hides are reservoirs of this pathogen. Bacteriophages present an attractive non-antibiotic strategy for control of Salmonella in beef. In
Yicheng Xie, Yicheng Xie, Tyler Thompson, Chandler O’Leary, Chandler O’Leary, Stephen Crosby, Quang X. Nguyen, Mei Liu, Jason J. Gill, Jason J. Gill   +9 more
doaj   +1 more source

A phage nucleus-associated RNA-binding protein is required for jumbo phage infection

Nucleic Acids Research
Abstract Large-genome bacteriophages (jumbo phages) of the proposed family Chimalliviridae assemble a nucleus-like compartment bounded by a protein shell that protects the replicating phage genome from host-encoded restriction enzymes and DNA-targeting CRISPR-Cas nucleases.
Eray Enustun, Emily G Armbruster, Jina Lee, Sitao Zhang, Brian A Yee, Kseniya Malukhina, Yajie Gu, Amar Deep, Jack T Naritomi, Qishan Liang, Stefan Aigner, Benjamin A Adler, Brady F Cress, Jennifer A Doudna, Vorrapon Chaikeeratisak, Don W Cleveland, Majid Ghassemian, Bogdan Bintu, Gene W Yeo, Joe Pogliano, Kevin D Corbett   +20 more
openaire   +4 more sources

Novel bacteriophages targeting wheat phyllosphere bacteria carry DNA modifications and single-strand breaks

Virus Research
The phyllosphere microbiome can positively or negatively impact plant health and growth, but we currently lack the tools to control microbiome composition.
Peter Erdmann Dougherty, Maja Schmidt Pedersen, Laura Milena Forero-Junco, Alexander Byth Carstens, Jos M. Raaijmakers, Leise Riber, Lars Hestbjerg Hansen   +6 more
doaj   +1 more source

The human oral phageome is highly diverse and rich in jumbo phages [PDF]

, 2020
AbstractUntil recently, the contribution of bacteriophages to the composition and function of the human microbiome has been largely overlooked. Recent developments in discovering novel bacteriophages from human metagenomes have been mostly focused on the gut.
Victoria R. Carr, Andrey Shkoporov, David Gomez-Cabrero, Peter Mullany, Colin Hill, David L. Moyes   +5 more
openaire   +1 more source

Isolation and Characterization of Two Novel Genera of Jumbo Bacteriophages Infecting Xanthomonas vesicatoria Isolated from Agricultural Regions in Mexico

Antibiotics
Bacterial spot is a serious disease caused by several species of Xanthomonas affecting pepper and tomato production worldwide. Since the strategies employed for disease management have been inefficient and pose a threat for environmental and human health,
Claudia Villicaña, Lucía M. Rubí-Rangel, Luis Amarillas, Luis Alberto Lightbourn-Rojas, José Armando Carrillo-Fasio, Josefina León-Félix   +5 more
doaj   +1 more source

Genome-wide identification of bacterial genes contributing to nucleus-forming jumbo phage infection. [PDF]

Nucleic Acids Res
Abstract The Chimalliviridae family of bacteriophages (phages) form a proteinaceous nucleus-like structure during infection of their bacterial hosts. This phage ‘nucleus’ compartmentalises phage DNA replication and transcription, and shields the phage genome from DNA-targeting defence systems such as CRISPR-Cas and restriction ...
Harding KR, Malone LM, Kyte NAP, Jackson SA, Smith LM, Fineran PC.   +5 more
europepmc   +3 more sources

Two asian jumbo phages, ϕRSL2 and ϕRSF1, infect Ralstonia solanacearum and show common features of ϕKZ-related phages

Virology, 2016
Jumbo phages infecting Ralstonia solanacearum were isolated in Thailand (ϕRSL2) and Japan (ϕRSF1). They were similar regarding virion morphology, genomic arrangement, and host range. Phylogenetic and proteomic tree analyses demonstrate that the ϕRSL2 and ϕRSF1 belong to a group of evolutionary related phages, including Pseudomonas phages ϕKZ, 201ϕ2-1 ...
Bhunchoth, Anjana, Blanc-Mathieu, Romain, Mihara, Tomoko, Nishimura, Yosuke, Askora, Ahmed, Phironrit, Namthip, Leksomboon, Chalida, Chatchawankanphanich, Orawan, Kawasaki, Takeru, Nakano, Miyako, Fujie, Makoto, Ogata, Hiroyuki, Yamada, Takashi   +12 more
openaire   +2 more sources

New Genera and Species of Caulobacter and Brevundimonas Bacteriophages Provide Insights into Phage Genome Evolution

Viruses
Previous studies have identified diverse bacteriophages that infect Caulobacter vibrioides strain CB15 ranging from small RNA phages to four genera of jumbo phages.
Bert Ely, Michael Hils, Aaron Clarke, Maegan Albert, Nadia Holness, Jacob Lenski, Tannaz Mohammadi   +6 more
doaj   +1 more source

Transcription Profiling of Bacillus subtilis Cells Infected with AR9, a Giant Phage Encoding Two Multisubunit RNA Polymerases

mBio, 2017
Bacteriophage AR9 is a recently sequenced jumbo phage that encodes two multisubunit RNA polymerases. Here we investigated the AR9 transcription strategy and the effect of AR9 infection on the transcription of its host, Bacillus subtilis.
Daria Lavysh, Maria Sokolova, Marina Slashcheva, Konrad U. Förstner, Konstantin Severinov   +4 more
doaj   +1 more source

Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance

Frontiers in Microbiology
Phages, which play a crucial role in regulating bacterial populations and evolution, have gained renewed attention as potential therapeutic agents especially in the face of rising antimicrobial resistance, such as in Klebsiella pneumoniae– a MDR pathogen
Chandrasekar Karthika, Nambiraman Malligarjunan, Nagaiah Hari Prasath, Shunmugiah Karutha Pandian, Shanmugaraj Gowrishankar   +4 more
doaj   +1 more source