Results 91 to 100 of about 6,513 (167)
Current Issues in Molecular BiologyHistone demethylases (HDMs) play a pivotal role in colorectal cancer (CRC) progression through dynamic epigenetic regulation. This review summarizes the role and therapeutic potential of HDM in CRC.
Yuanbin Liu +3 more
doaj +1 more source
A Targeted RNA Interference Screen Reveals Novel Epigenetic Factors That Regulate Herpesviral Gene Expression [PDF]
, 2013 Herpes simplex virus (HSV) utilizes and subverts host chromatin mechanisms to express its lytic gene products in mammalian cells. The host cell attempts to silence the incoming viral genome by epigenetic mechanisms, but the viral VP16 and ICP0 proteins ...
Bagul, Mukta +7 more
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European Journal of Immunology, Volume 55, Issue 10, October 2025.This review discusses the principles underlying the interplay of epigenetics, metabolism, and post‐transcriptional regulation of gene expression mediated by RNA‐binding proteins, both in the nucleus and in the cytoplasm. Particularly, it focuses on the relevance that these circuits have in lymphocytes and autoimmunity.
Francesca Rossi, Martin Turner
wiley +1 more source
Histone Methylation in the Nervous System: Functions and Dysfunctions [PDF]
, 2018 Chromatin remodeling is a key epigenetic process controlling the regulation of gene transcription. Local changes of chromatin architecture can be achieved by post-translational modifications of histones such as methylation, acetylation, phosphorylation ...
Jacob, Claire, Pattaroni, Céline
core
Runt-Related Transcription Factor 2 Induction During Differentiation of Wharton's Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT-Rich Interactive Domain 1B Histone Demethylase [PDF]
, 2017 Indexación: ScopusNovel bone regeneration approaches aim to obtain immature osteoblasts from somatic stem cells. Umbilical cord Wharton's jelly mesenchymal stem cells (WJ-MSCs) are an ideal source for cell therapy. Hence, the study of mechanisms involved
Amini +67 more
core +2 more sources
Guangdong nongye kexue【Objective】Demethylation mediated by histone demethylases (HDMs) containing the JMJ domain plays a crucial role in chromatin conformation and the physiological activities it governs, such as replication and transcription.
Yan LIU +9 more
doaj +1 more source
Ecotoxicology and Environmental SafetyCadmium (Cd) pollution in soil poses a global concern due to its serious impacts on human health and ecological security. In plants, tremendous efforts have been made to identify some key genes and pathways in Cd stress responses. However, studies on the
Shuai Yu +12 more
doaj +1 more source
Dissecting the epigenetic landscapes of hematopoiesis and fission yeast. [PDF]
, 2014 The genome of eukaryotic cells is stored in the nucleus as chromatin, a DNA-protein complex that serves to compact and protect the DNA molecules. The basic unit of chromatin is the nucleosome composed of DNA wrapped around a histone protein core ...
Rönnerblad, Michelle
core +1 more source
To Erase or Not to Erase: Non-Canonical Catalytic Functions and Non-Catalytic Functions of Members of Histone Lysine Demethylase Families [PDF]
Histone lysine demethylases (KDMs) play an essential role in biological processes such as transcription regulation, RNA maturation, transposable element control, and genome damage sensing and repair.
Di Nisio, Elena +3 more
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Molecular CancerBreast cancer (BC) is the most frequent malignant cancer diagnosis and is a primary factor for cancer deaths in women. The clinical subtypes of BC include estrogen receptor (ER) positive, progesterone receptor (PR) positive, human epidermal growth factor
Chang-Yun Li +4 more
doaj +1 more source