Results 101 to 110 of about 6,610 (186)

Dynamic protein methylation in chromatin biology [PDF]

, 2008
Post-translational modification of chromatin is emerging as an increasingly important regulator of chromosomal processes. In particular, histone lysine and arginine methylation play important roles in regulating transcription, maintaining genomic ...
S. S. Ng, W. W. Yue, U. Oppermann, R. J. Klose, A. Kossel, R.D. Kornberg, T. Agalioti, S. Chakravarthy, S.D. Taverna, T. Jenuwein, C. Martin, M.T. Bedford, R.J. Klose, S.L. Berger, B.E. Bernstein, T. Kouzarides, W. Reik, B.M. Turner, Q. Feng, H.H. Ng, F. Leeuwen van, B.D. Strahl, H. Wang, H.C. Beck, B.A. Garcia, A.H. Peters, R.R. Cocklin, L. Zhang, B.A. Garcia, C.A. Hazzalin, B.D. Strahl, G. Liang, K.P. Nightingale, J.J. Pesavento, D. Phanstiel, S. Rea, C.D. Allis, Y. Tanaka, X.J. Sun, G.V. Rayasam, J.W. Edmunds, O. Bell, M.D. Shahbazian, R.N. Laribee, J.S. Lee, A. Kirmizis, J.E. Dodge, K. Hayashi, J.K. Kurash, D. O’Carroll, A.H. Peters, G. Steele-Perkins, B.D. Yu, R.J. Jaju, P.M. Ayton, D. Greiner, S. Kubicek, J. Wysocka, H. Li, A.J. Bannister, M. Lachner, J. Nakayama, F. Lan, S.K. Ooi, A.J. Ruthenburg, Y. Huang, J. Lee, A.G. Matthews, S. Ramon-Maiques, R.E. Collins, M.V. Botuyan, P. Trojer, J. Min, J.F. Couture, Z. Han, A.J. Ruthenburg, A. Schuetz, P. Byvoet, J.A. Duerre, Y. Shi, Y. Tsukada, P. Stavropoulos, Y. Chen, M. Yang, S.S. Ng, J.F. Couture, Z. Chen, Z. Chen, M. Yang, T. Swigut, R.J. Klose, Y. Shi, P.A. Cloos, B. Chang, Y. Wang, G.L. Cuthbert, B. Perillo, R. Metivier, S. Kangaspeska, B. Holmquist, M. Koivusalo, F.J. Iborra, K. Yamane, R.J. Klose, R.J. Klose, D. Frescas, F. Lan, F. Santa De, K. Agger, S. Iwase, M. Wissmann, J.R. Whetstine, K. Yamane, M.G. Lee, P.A. Cloos, M. Tahiliani, Y.H. Loh, Y. Okada, K. Zhang, M.D. Huq, A. Kouskouti, R.L. Houtz, E.W. Thompson, J. Huang, X. Shi, L. Feng, S. Chuikov, J. Huang, A. Olsson, B. Rao, D.K. Pokholok, T.S. Mikkelsen, A. Barski, M.G. Guenther, T. Xiao, X.D. Zhao, G. Pan, B.E. Bernstein, R. Cao, J. Muller, A. Kuzmichev, I. Issaeva, K. Jepsen, E. Guccione, D. Hyllus   +144 more
core   +1 more source

Identification and Expression Analysis of the JMJ Histone Demethylase Family Genes in Lagenaria siceraria

Guangdong nongye kexue
【Objective】Demethylation mediated by histone demethylases (HDMs) containing the JMJ domain plays a crucial role in chromatin conformation and the physiological activities it governs, such as replication and transcription.
Yan LIU, Chaoran YU, Hongmei YIN, Fengyu HUANG, Ying WANG, Jinsen CAI, Min WANG, Zhongyi ZHAO, Songguang YANG, Qingwu PENG   +9 more
doaj   +1 more source

Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication [PDF]

, 2015
Renal cell tumors (RCTs) are the most lethal of the common urological cancers. The widespread use of imaging entailed an increased detection of small renal masses, emphasizing the need for accurate distinction between benign and malignant RCTs, which is ...
Abrahams NTP, Ana Sílvia Pires-Luís, Bruno M Costa, Carmen Jerónimo, Céline S Gonçalves, Ferlay J SI EM, Filipa Quintela Vieira, Francisco Lobo, Jorge Oliveira, Luís Antunes, Márcia Vieira-Coimbra, Paula C Dias, Pedro Costa-Pinheiro, Rui Henrique, Rui Silva-Santos   +14 more
core   +3 more sources

Dynamic transcriptome profiling revealed a key gene ZmJMJ20 and pathways associated with cadmium stress in maize

Ecotoxicology and Environmental Safety
Cadmium (Cd) pollution in soil poses a global concern due to its serious impacts on human health and ecological security. In plants, tremendous efforts have been made to identify some key genes and pathways in Cd stress responses. However, studies on the
Shuai Yu, Jialun Zhu, Yanzhe Yin, Xiaoyu Zhang, Yuxin Dai, Yupeng Xing, Xipeng Cheng, Ao Zhang, Cong Li, Yanshu Zhu, Yanye Ruan, Xiaomei Dong, Jinjuan Fan   +12 more
doaj   +1 more source

KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges

Molecular Cancer
Breast cancer (BC) is the most frequent malignant cancer diagnosis and is a primary factor for cancer deaths in women. The clinical subtypes of BC include estrogen receptor (ER) positive, progesterone receptor (PR) positive, human epidermal growth factor
Chang-Yun Li, Wanhe Wang, Chung-Hang Leung, Guan-Jun Yang, Jiong Chen   +4 more
doaj   +1 more source

To Erase or Not to Erase: Non-Canonical Catalytic Functions and Non-Catalytic Functions of Members of Histone Lysine Demethylase Families [PDF]

Histone lysine demethylases (KDMs) play an essential role in biological processes such as transcription regulation, RNA maturation, transposable element control, and genome damage sensing and repair.
Di Nisio, Elena, Licursi, Valerio, Manzini, Valeria, Negri, Rodolfo   +3 more
core   +1 more source

The Functions and Mechanisms of Histone Demethylase JMJD1A in Urinary Bladder Cancer Development [PDF]

, 2015
JMJD1A（JumonjiCdomain-containing1A），又名JHDM2A，KDM3A，是一种组蛋白去甲基化酶，可以特异性去除H3K9位点的一甲基化和二甲基化，在组蛋白甲基化修饰中起到重要作用。JMJD1A表达受到低氧诱导因子HIF-1α（hypoxia-induciblefactor1α）的调节，并且参与到肿瘤细胞对低氧环境的适应性调节过程中。 膀胱癌是世界范围内高发和高致死率的恶性肿瘤之一。已有报道JMJD1A在膀胱癌肿瘤组织中高表达，但是JMJD1A在膀胱癌的发生发展机制尚不清楚 ...
秦丽萍
core  

Small molecule inhibitor of jumonji C domain–containing histone demethylases (JHDMs) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Quantitative analysis of jumonji C domain–containing histone demethylase (JHDM)-targeting compounds [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Epigenome Modifying Tools In Asthma [PDF]

, 2015
Adcock,, Brook, PO, Durham, AL, Perry, M
core   +1 more source