Pests and diseases affecting potato landraces and bred varieties grown in Peru under indigenous farming system [PDF]
, 2015 The major pests and diseases were identified and quantified on thirteen potato landraces and three bred varieties cultivated in Peru. Late blight (Phytophthora infestans) was the primary biotic constraint affecting plants before flowering with an average
Andrade-Piedra, J.L. +4 more
core +1 more source
Influence of ethnicity on the distribution of genetic polymorphisms associated with risk of chronic liver disease in South American populations [PDF]
, 2015 BACKGROUND: The global burden of chronic liver disease is rising. Besides environmental, behavioral, viral and metabolic factors, genetic polymorphisms in patatin-like phospholipase-3 (PNPLA3) and vitamin D receptor (VDR) genes have been related to the ...
Argibay, Pab lo +12 more
core +1 more source
Nature Communications, 2018 The five known New World hemorrhagic fever arenaviruses use the same entry receptor, but their viral glycoproteins are markedly different. Here, the authors isolate monoclonal antibodies from a Junin virus vaccinated person that cross-neutralize Machupo ...
Lars E. Clark +12 more
doaj +1 more source
Caracterizacion sintomatologica y molecular del virus de la mancha anillada del papayo (PRSV) que infecta Carica papaya L. en el norte del Peru [PDF]
, 2015 The objective of present study was symptomatic and molecular characterization of the virus that infects Carica papaya L. in areas of northern Peru. To do this, of different fields were collected leaves of C.
Carbajal, S. +4 more
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Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. [PDF]
PLoS Neglected Tropical Diseases, 2011 Lassa and Junín viruses are the most prominent members of the Arenaviridae family of viruses that cause viral hemorrhagic fever syndromes Lassa fever and Argentine hemorrhagic fever, respectively.
Michelle Mendenhall +6 more
doaj +1 more source
Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus [PDF]
, 2019 Interferon response suppression by the respiratory syncytial virus relies on two unique nonstructural proteins, NS1 and NS2, that interact with cellular partners through high-order complexes.
Alonso, Leonardo Gabriel +9 more
core +1 more source
Regional differences and hantavirus pulmonary syndrome (an emerging and tropical disease in Argentina) [PDF]
, 2000 Se describen algunos factores que habrían favorecido a caracterizar la expresión del Síndrome Pulmonar por Hantavirus en Argentina. Estos factores muestran diversos orígenes que van desde los procesos de ocupación del espacio y de producción, la ...
Esquivel, María Laura +4 more
core +3 more sources
Vaccine Candidates against Arenavirus Infections
Vaccines, 2023 The viral family Arenaviridae contains several members that cause severe, and often lethal, diseases in humans. Several highly pathogenic arenaviruses are classified as Risk Group 4 agents and must be handled in the highest biological containment ...
Takeshi Saito +5 more
doaj +1 more source
Bunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidase [PDF]
, 2016 This study was supported by Wellcome Trust Grant 099220/B/12/Z (to R.M.E.) and Grant 094476/Z/10/Z that funded the purchase of the TripleTOF 5600 mass spectrometer at the Biomedical Sciences Research Complex (BSRC) of University of St. Andrews.Bunyamwera
Botting, Catherine Helen +7 more
core +2 more sources
Role of the ERK1/2 Signaling Pathway in the Replication of Junín and Tacaribe Viruses
Viruses, 2018 We have previously shown that the infection of cell cultures with the arenaviruses Junín (JUNV), Tacaribe (TCRV), and Pichindé promotes the phosphorylation of mitogen-activated protein kinases (MAPKs) extracellular signal-regulated kinases ...
Jesús E. Brunetti +5 more
doaj +1 more source