Results 181 to 190 of about 5,614 (215)

Inapparent Infections with Junin Virus among Laboratory Workers

Journal of Infectious Diseases, 1978
Mercedes C. Weissenbacher, Maria E. Grela, Marta S. Sabattini, J. I. Maiztegui, Celia E. Coto, M. J. Frigerio, P. M. Cossio, Adriana S. Rabinovich, and J. G. Barrera Oro From the Cdtedra de Microbiologia y Parasitologia, Facultad de Medicina, and Cdtedra de Microbiologia, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos ...
M C, Weissenbacher, M E, Grela, M S, Sabattini, J I, Maiztegui, C E, Coto, M J, Frigerio, P M, Cossio, A S, Rabinovich, J G, Barrera Oro   +8 more
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Junin Virus Infection of Callithrix Jacchus: Pathologic Features

The American Journal of Tropical Medicine and Hygiene, 1983
Infection of Callithrix jacchus, a New World primate, with the prototype strain of Junin virus produced a severe disease. The animals developed multifocal hemorrhages and characteristic microscopic lesions such as meningoencephalitis, interstitial pneumonia, lymphocytic depletion of lymphatic tissue, hepatocytic necrosis, and a variable decrease in ...
P H, González, R P, Laguens, M J, Frigerio, M A, Calello, M C, Weissenbacher   +4 more
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In vitro selection of Junin virus antigenic variants

Archives of Virology, 1993
The establishment of an experimental persistent infection with Junin virus, the aetiological agent of argentine hemorrhagic fever, involves the emergence of antigenic variants in brain and blood of the cricetid Calomys musculinus. We demonstrate that antigenic variants can also be isolated in vitro under the selective pressure of polyclonal antibodies ...
L E, Alché, C E, Coto
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Calomys callidus as a potential junin virus reservoir

Journal of Medical Virology, 1989
AbstractThe present study investigated whether C. callidus, a species belonging to the Calomys genus, is capable of developing experimentally a persistent Junin virus (JV) infection. Newborn and adult cricetids were inoculated with the attenuated XJ‐Clone 3 strain of JV by intracerebral or mucosal route. The present results indicate that the species is
C, Videla, A, Kajon, G, Carballal, M, Weissenbacher   +3 more
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An antibody for fighting Junin virus

C&EN Global Enterprise, 2016
Argentine hemorrhagic fever was discovered in the 1950s, and it hasn’t spread beyond Argentina’s borders since. But the illness’s mortality rate—which can be as high as 30%—has public health officials worried. The fever is caused by Junin virus and transmitted by rodents through their saliva and droppings, so it could spread outside its current range ...
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Involvement of vacuolar proton ATPase in Junin virus multiplication

Archives of Virology, 2001
The role of vacuolar-proton ATPase (V-H+ ATPAse) on Junin virus (JV) replication was evaluated by analyzing the effect of specific inhibitors of the enzyme activity on different steps of virus multiplication cycle. The presence of the macrolide antibiotics bafilomycin A1 and concanamycin A during the first two hours of infection caused a significant ...
V, Castilla, L M, Palermo, C E, Coto
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Junin virus access to CNS by extraneural rat inoculation

Journal of Medical Virology, 1986
AbstractThis study was carried out to determine the pathways along which two strains of Junin virus (JV), the pathogenic XJV and the attenuated XJC13V, reach the CNS following IP inoculation of 2‐day‐old rats. A sequential study of infectivity and antigen distribution in peritoneal macrophages, spleen, and brain was performed.
G D, Lerman, J L, Blejer, J R, Oubiña, G, Carballal, M R, Nejamkis   +4 more
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Contrasuppressor cells induced by Junin virus.

Immunology, 1990
Intracerebral inoculation of Junin virus (JV) in all susceptible mouse models available induces a lethal meningoencephalitis compatible with a delayed-type hypersensitivity (DTH) immune response. In contrast, adult BALB/c mice prove resistant to infection and no DTH response is seen.
O E, Campetella, N V, Galassi, H A, Barrios   +2 more
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Photodynamic inactivation of Junin virus

Medical Microbiology and Immunology, 1986
M, Fernández Cobo, E L, Pasian, Z M, de Martínez Segovia   +2 more
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Heterogeneity of Junin virus strains

Medical Microbiology and Immunology, 1986
R H, Kenyon, K T, McKee, J I, Maiztegui, D E, Green, C J, Peters   +4 more
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