Results 21 to 30 of about 62,486 (251)

Physiological Responses of Jurkat Lymphocytes to Simulated Microgravity Conditions [PDF]

International Journal of Molecular Sciences, 2019
The presence of microgravity conditions deeply affects the human body functions at the systemic, organ and cellular levels. This study aimed to investigate the effects induced by simulated-microgravity on non-stimulated Jurkat lymphocytes, an immune cell phenotype considered as a biosensor of the body responses, in order to depict at the cellular level
Morabito, Caterina, Lanuti, Paola, Caprara, Giusy A., Marchisio, Marco, Bizzarri, Mariano, Guarnieri, Simone, Mariggiò, Maria A.   +6 more
openaire   +3 more sources

Biological particle manipulation: An example of Jurkat enrichment

10th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2015
Dielectrophoresis‐based separation of microparticles and living cells are studied with computational and experimental methods. The flow behaviours of particles are modelled and simulated using COMSOL Multiphysics 4.3a software (COMSOL Ltd). Lab‐on‐a‐chip devices having a titanium (Ti) interdigitated electrode layer on a glass substrate and a PDMS ...
Emre Altinagac, Safiye Selen Ozcan, Yavuz Genc, Hüseyin Kizil, Levent Trabzon   +4 more
openaire   +6 more sources

Цитопротекторная активность феновина в митоген-активированных клетках Jurkat [PDF]

, 2012
Department of Anatomy, Tbilisi State Medical UniversityThe aim of the study: to establish the cytoprotective ability of the application of Phenovine to mitogen-activated Jurkat cells’ modeling systems.
Sanikidze, T., Dgebuadze, M., Intskirveli, N., Chkhikvishvili, I., Ratiani, T., Sharashenidze, G., Ratiani, L.   +6 more
core   +1 more source

The Continuous Concentration of Particles and Cancer Cell Line Using Cell Margination in a Groove-Based Channel

Micromachines, 2017
In the capillary venules, blood cells auto-separate with red blood cells aggregating near the centre of vessel and the nucleated cells marginating toward the wall of vessel. In this experiment, we used cell margination to help enrich the Jurkat cells via
Sheng Yan, Dan Yuan, Qianbin Zhao, Jun Zhang, Weihua Li   +4 more
doaj   +1 more source

GABAA receptor plasticity in Jurkat T cells

Biochimie, 2013
GABAA receptors (GABAAR) mediate inhibitory neurotransmission in the human brain. Neurons modify subunit expression, cellular distribution and function of GABAAR in response to different stimuli, a process named plasticity. Human lymphocytes have a functional neuronal-like GABAergic system with GABAAR acting as inhibitors of proliferation.
Dionisio, Leonardo Raul, Arias, Verònica Cecilia, Bouzat, Cecilia Beatriz, Esandi, María del Carmen   +3 more
openaire   +3 more sources

Oxidative stress signalling in the apoptosis of Jurkat T‐lymphocytes [PDF]

Journal of Cellular Biochemistry, 2001
AbstractThe pathways of transduction of oxidative stress signals have been studied using the Jurkat T cell model. The oxidative stress was induced by exposure of the cells to 100 μM H2O2. DNA damage was detected within 15 min after commencement of treatment. DNA damage repair occurred within about 1 h in cells exposed to oxidative stress for 15 min. In
R. Chiaramonte, E. Bartolini, P. Riso, E. Calzavara, D. Erba, G. Testolin, P. Comi, G. V. Sherbet   +7 more
openaire   +3 more sources

Exploring the Immunomodulatory Effects of Liposomal Daunorubicin on Jurkat Cells: A Study of Apoptosis and Gene Expression in Co-Cultured MDA-MB-231 Cells [PDF]

Pharmaceutical Sciences
Background: Breast cancer represents a significant aspect of women’s health, constituting approximately 30% of cancers affecting them globally, with a mortality rate of around 15%.
Malik Kareem Shanan, Amir Arasteh, Mahsa Mohamad Amoli, Mehdi Ebrahimi   +3 more
doaj   +1 more source

Effects of Cisplatin on Mitochondrial Function in Jurkat Cells

Chemical Research in Toxicology, 2004
In this work, we measured the effects of pharmacological concentrations of cisplatin (cis-diaminedichloroplatinum II) on mitochondrial function, cell viability, and DNA fragmentation in Jurkat cells. The exposure of cells to 0-25 microM cisplatin for 3 h had no immediate effect on cellular mitochondrial oxygen consumption, measured using a palladium ...
Tacka, Kirk, Dabrowiak, James C, Goodisman, Jerry, Penefsky, Harvey S, Souid, Abdul Kader   +4 more
openaire   +3 more sources

Responses to membrane potential-modulating ionic solutions measured by magnetic resonance imaging of cultured cells and in vivo rat cortex

eLife
Membrane potential plays a crucial role in various cellular functions. However, existing techniques for measuring membrane potential are often invasive or have limited recording depth.
Kyeongseon Min, Sungkwon Chung, Seung-Kyun Lee, Jongho Lee, Phan Tan Toi, Daehong Kim, Jung Seung Lee, Jang-Yeon Park   +7 more
doaj   +1 more source

Potentiation of Bleomycin in Jurkat Cells by Fungal Pycnidione

Biological and Pharmaceutical Bulletin, 2012
Most cancer cells have mutations in genes at the G1 checkpoint and repair DNA only in the G2 phase; therefore, the G2 checkpoint is a potential target to develop novel therapy. In the course of screening, a known compound, pycnidione, was isolated from the fungal culture broth of Gloeotinia sp. FKI-3416.
Kaneko, Mayumi, Matsuda, Daisuke, Ohtawa, Masaki, Fukuda, Takashi, Nagamitsu, Tohru, Yamori, Takao, Tomoda, Hiroshi   +6 more
openaire   +3 more sources