Results 31 to 40 of about 62,486 (251)

Effect of 2-isobutyl-4,6-dimethyl-5-oxypyrimidine hydrochloride with antitumor activity on the cell cycle phases in the Jurkat model

Фармакокинетика и Фармакодинамика
Introduction. Evaluating the ability of novel antitumor compounds to arrest specific phases of the cell cycle is a key step in their preclinical characterization for chemotherapeutic application.
R. V. Zhurikov, A. A. Sokolovskaya, L. P. Kovalenko, L. G. Kolik   +3 more
doaj   +1 more source

Apoptosis induction in Jurkat cells and sCD95 levels in women's sera are related with the risk of developing cervical cancer

BMC Cancer, 2008
Background Currently, there is clear evidence that apoptosis plays an important role in the development and progression of tumors. One of the best characterized apoptosis triggering systems is the CD95/Fas/APO-1 pathway; previous reports have ...
Bravo-Cuellar Alejandro, del Toro-Arreola Susana, Morgan-Villela Gilberto, Ortiz-Lazareno Pablo C, Lerma-Diaz Jose M, Hernandez-Flores Georgina, Olimon-Andalon Vicente, Romero-Ramos Jose E, Aguilar-Lemarroy Adriana, Jave-Suarez Luis F   +9 more
doaj   +1 more source

Modulatory Impact of Lamiaceae Metabolites on Apoptosis of Human Leukemia Cells

Frontiers in Pharmacology, 2022
Lamiaceae species are rich sources of biologically active compounds which have been applied in medicine since ancient times. Especially their antineoplastic properties have been thoroughly studied with respect to their putative application in ...
Izabela Berdowska, Bogdan Zieliński, Małgorzata Matusiewicz, Izabela Fecka   +3 more
doaj   +1 more source

Biophysical Investigation of the Ironome of Human Jurkat Cells and Mitochondria [PDF]

Biochemistry, 2012
The speciation of iron in intact human Jurkat leukemic cells and their isolated mitochondria was assessed using biophysical methods. Large-scale cultures were grown in medium enriched with (57)Fe citrate. Mitochondria were isolated anaerobically to prevent oxidation of iron centers.
Nema D, Jhurry, Mrinmoy, Chakrabarti, Sean P, McCormick, Gregory P, Holmes-Hampton, Paul A, Lindahl   +4 more
openaire   +2 more sources

Validation of the Jurkat-RORγt-LBD stable cell lines.

, 2015
RORγt+-Jurkat (RORγt-LBD positive Jurkat cells) and RORγt--Jurkat (RORγt-LBD negative Jurkat cells) stable cells (1x105) were seeded onto 12-well plates and incubated in 1 mL RPMI 1640 complete medium overnight.
Qingfeng Ding (795498), Bolan Yu (514237), Zhaofeng Huang (124948), Mei Zhao (177004), Chuan Bai (548830)   +4 more
core   +1 more source

Construction of Jurkat/CAR T-cells specific to CD19.

, 2020
a DNA map of pLECE3-19BBz lentivirus vector. b CAR expression on Jurkat T-cells. Jurkat T-cells were either left alone (left) or transduced with pLECE-19BBz lentiviruses (right).
Jin Hwa Chung (8259699), Jin-Sook Ryu (732108), Sang-Jin Lee (503626), Suk Hyun Lee (8259696), Hyori Kim (819938), Sang Ju Lee (2515072), Kyungho Choi (513597), Seung Jun Oh (2473048), Seog-Young Kim (297940), Eun Hye Cho (8259702), Ji-Min Ju (8259705), Junho Chung (171648), Hyunsu Soh (579311), Joong Hyuk Sheen (8259708)   +13 more
core   +1 more source

Jurkat/A4 cells with multidrug resistance exhibit reduced sensitivity to quercetin [PDF]

, 2010
Background: While multidrug resistance of cancer cells is a well-known phenomenon, little is known on the cross resistance between cytotoxic chemotherapeutical agents and unrelated substances such as natural flavonoids.
Philchenkov, A., Zavelevich, M., Blokhin, D., Savinska, L.   +3 more
core   +2 more sources

Minerval induces apoptosis in Jurkat and other cancer cells [PDF]

Journal of Cellular and Molecular Medicine, 2010
AbstractMinerval is an oleic acid synthetic analogue that impairs lung cancer (A549) cell proliferation upon modulation of the plasma membrane lipid structure and subsequent regulation of protein kinase C localization and activity. However, this mechanism does not fully explain the regression of tumours induced by this drug in animal models of cancer ...
Llado, Victoria, Gutierrez, Antonio, Martínez, Jordi, Casas, Jesús, Terés, Silvia, Higuera, Mónica, Galmés, Antonio, Saus, Carles, Besalduch, Joan, Busquets, Xavier, Escribá, Pablo V   +10 more
openaire   +2 more sources

AID is transcribed in the Jurkat-AID and not in the control Jurkat cell line.

, 2013
AID transcription was monitored with RT-PCR in a control cell line, Jurkat, and in a Jurkat-AID cell line stably transfected with AID. A Burkitt lymphoma cell line Ramos constitutively expressing AID was used as a positive control for AID expression ...
Tihana Jovanic (84063), Géraldine Attal-Bonnefoy (84065), François Rougeon (84067), Olivier Leclercq (84066), Benjamin Roche (84064)   +4 more
core   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source