Results 151 to 160 of about 43,474 (209)

Protocol to establish endogenous knockins in Jurkat T-ALL cells using CRISPR-Cas9-mediated homology-directed repair. [PDF]

open access: yesSTAR Protoc
Costa JR   +10 more
europepmc   +1 more source

Efficient discovery of an agonistic anti-OX40 nanobody by epitope-directed approach to address enrichment-driven epitope bias. [PDF]

open access: yesJ Immunother Cancer
Iemura T   +10 more
europepmc   +1 more source

NETs drive CD4⁺ T cell dysfunction in sepsis via mitochondrial ROS and impaired calcium signalling. [PDF]

open access: yesMol Med
Li H   +15 more
europepmc   +1 more source

A tumor suppressor role of the miR-15b/16-2 cluster in T-cell acute lymphoblastic leukemia.

open access: yesBlood
Toribio ML   +8 more
europepmc   +1 more source
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Jurkat T Cells and Development of the T-Cell Receptor Signalling Paradigm

Nature Reviews Immunology, 2004
Twenty years of investigation have yielded a detailed view of the signalling machinery engaged by T-cell receptors (TCRs). Many of the fundamental insights into TCR signalling came from studies carried out with transformed T-cell lines. Perhaps the best known of these model systems is the Jurkat leukaemic T-cell line, and here we review some of the key
Robert T Abraham
exaly   +3 more sources

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