Results 61 to 70 of about 2,708,099 (339)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Rethinking Just Transition in Investment Law Perspective: Incentives against Climate Crisis between Sustainability, Economic Security, and Strategic Industrial Planning

Laws
With the expression “Just transition”, the European Commission refers to a new development model to bring in the environmental and digital transition “leaving no one behind”.
Sara Pugliese
doaj   +1 more source

A Just Transition

European Journal of Workplace Innovation
Responding to the climate emergency, governments have pledged to deliver a net zero future. Delivery requires more green jobs and a just transition of good jobs and labour market inclusivity. The problem is that there is no agreed methodology for classifying green jobs.
Carolyn Snell, Lucie Middlemiss, Kelli Kennedy, Tania Carregha, Anne Owen, Samanthi Theminimulle   +5 more
  +4 more sources

Temperature Dependence of the Flux Line Lattice Transition into Square Symmetry in Superconducting LuNi$_2$B$_2$C

, 2001
We have investigated the temperature dependence of the H || c flux line lattice structural phase transition from square to hexagonal symmetry, in the tetragonal superconductor LuNi_2B_2C (T_c = 16.6 K).
A. B. Abrahamsen, A. B. Abrahamsen, B. Rosenstein, D. K. Christen, D. K. Christen, D. McK. Paul, I. Affleck, J. Schelten, K. Mortensen, K. O. Cheon, M. Ichioka, M. R. Eskildsen, M. R. Eskildsen, M. R. Eskildsen, M. R. Eskildsen, M. Yethiraj, M. Yethiraj, N. H. Andersen, P. C. Canfield, P. C. Canfield, P. L. Gammel, P. L. Gammel, U. Klein, U. Yaron, V. G. Kogan, V. G. Kogan, V. G. Kogan, V. G. Kogan, Y. DeWilde, Z. D. Hao   +29 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A Roadmap for Michigan’s EV Future: An Assessment of the Employment Effects and Just Transition Needs [PDF]

, 2023
Devashree Saha, Joel Jaeger, Sujata Rajpurohit, Evana Said, John Laitner   +4 more
openalex   +1 more source

New high magnetic field phase of the frustrated $S=1/2$ chain compound LiCuVO$_4$

, 2010
Magnetization of the frustrated $S=1/2$ chain compound LiCuVO$_4$, focusing on high magnetic field phases, is reported. Besides a spin-flop transition and the transition from a planar spiral to a spin modulated structure observed recently, an additional ...
A. F. Andreev, A. I. Smirnov, A. K. Kolezhuk, A. K. Kolezhuk, A. Prokofiev, A. V. Chubukov, A. V. Prokofiev, A. V. Prokofiev, B. J. Gibson, D. V. Dmitriev, F. Heidrich-Meisner, H. T. Ueda, H. Yamaguchi, H.-A. Krug von Nidda, J. Sudan, K. Omura, L. E. Svistov, M. Blume, M. E. Zhitomirsky, M. Enderle, M. G. Banks, M. Hagiwara, M. Hagiwara, N. Büttgen, N. Büttgen, P. G. Gennes de, R. O. Kuzian, S. Kimura, T. Fujita, T. Hikihara, T. Nagamiya, Z. Honda   +31 more
core   +1 more source

Derivation of the Semi-circle Law from the Law of Corresponding States [PDF]

, 1999
We show that, for the transition between any two quantum Hall states, the semi-circle law and the existence of a duality symmetry follow solely from the consistency of the law of corresponding states with the two-dimensional scaling flow. This puts these
A. M. Dykhne, A. M. M. Pruisken, B. Huckelstein, B. P. Dolan, B. P. Dolan, Brian P. Dolan, C. A. Lütken, C. A. Lütken, C. A. Lütken, C. P. Burgess, C. P. Burgess, C. P. Burgess, D. E. Khmel’nitskii, D. Shahar, D. Shahar, E. Abrahams, E. T. Whittaker, H. P. Wei, I. Ruzin, J. K. Jain, J. K. Jain, L. Engel, M. Hilke, M. P. A. Fisher, M.-C. Cha, R. A. Rankin, R. B. Laughlin, R. Laughlin, Rim Dib, S. Kivelson, S. L. Sondhi, Y. Georgelin   +31 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source