Results 111 to 120 of about 1,185,148 (303)

From Hiroshima to Baghdad: Military Hegemony versus Just Military Preparedness [PDF]

open access: yes, 2009
In this paper I question the morality of U.S. military supremacy or hegemony in terms of what constitute the legitimate use of military force and the proper preparation for using such force.
van der Linden, Harry
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Еволюція феміністичного дискурсу війни: від антимілітаризму до етики піклування (The Evolution of Feminist Discourse of War From Antimilitarism to Ethics of Care) [PDF]

open access: yes, 2015
У статті проаналізовано феміністичний дискурс війни та його еволюція від антимілітаризму до етики піклування. Підкреслюється, що, спираючись на теорію справедливої війни та відходячи від суто гендерних ідентичностей, сучасні феміністки ...
Цимбал, Т. (T. Tsymbal)
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

La guerre en Irak peut-elle être justifiée comme un cas d’intervention humanitaire? [PDF]

open access: yesLes Ateliers de l’Ethique, 2006
Most current criticisms against the intervention in Iraq have tackled the two justifications articulated by the members of the coalition:(1) that the United States had to neutralize the threats that Iraq generated for their own security and to the ...
Stéphane Courtois
doaj  

Conceptions of War in Islamic Legal Theory and Practice [PDF]

open access: yes, 2007
The term Jihad, meaning Muslim ‘holy war,’ is a powerful symbol in contemporary society, signifying not only radical violence but the clash of Islamic and Western societies.
Pettygrove, Margaret
core   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

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