Results 11 to 20 of about 54,427 (263)

Endocrine and metabolic comorbidities in juvenile-onset systemic lupus erythematosus

Frontiers in Medicine
Background and aimsJuvenile-onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease affecting individuals under 18, causing multi-system impairment.
Su Jin Park, Moon Bae Ahn, Dae Chul Jeong   +2 more
doaj   +4 more sources

Autoantibody-based subgroups and longitudinal seroconversion in juvenile-onset systemic lupus erythematosus

Lupus Science and Medicine, 2023
Objective To explore the clinical value of autoantibody-based subgroup framework and the trend of autoantibody fluctuation in juvenile-onset SLE (JSLE).Methods Eighty-seven patients with JSLE were retrospectively collected and divided into subgroups via ...
Zhen Yang, Fei Ding, Chenxi Liu, Jingyi Lu, Hua Huang, Shengfang Bao, Yingying Jin, Xuemei Xu, Yanliang Jin   +8 more
doaj   +4 more sources

Associations of Raynaud's Phenomenon in Juvenile Onset Systemic Lupus Erythematosus

Van Tıp Dergisi
INTRODUCTION: Raynaud's phenomenon (RP) is associated with mild disease in adults with systemic lupus erythematosus (SLE). Although RP is more frequently reported in juvenile onset SLE (jSLE) clinical associations were not studied.
Özge Baba, Hakan Kısaoğlu, Mukaddes Kalyoncu   +2 more
doaj   +3 more sources

Musculoskeletal symptoms in juvenile onset systemic lupus erythematosus

Современная ревматология, 2023
In juvenile onset systemic lupus erythematosus (SLE), musculoskeletal involvement is one of the most common manifestations. Musculoskeletal symptoms may be due to disease activity itself, organ damage due to SLE activity, drug exposure, or comorbidities.
M. I. Kaleda, A. N. Arefieva, I. P. Nikishina   +2 more
doaj   +2 more sources

Vasculitis in Juvenile-Onset Systemic Lupus Erythematosus [PDF]

Frontiers in Pediatrics, 2019
Juvenile-onset systemic lupus erythematosus (JSLE) is a rare, heterogeneous multisystem autoimmune disease that can affect any organ, and present with diverse clinical and serological manifestations. Vasculitis can be a feature of JSLE.
Eve M. D. Smith, Eve M. D. Smith, Hanna Lythgoe, Christian M. Hedrich, Christian M. Hedrich   +4 more
doaj   +4 more sources

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus

Научно-практическая ревматология, 2020
Neuropsychiatric disorders in juvenile-onset systemic lupus erythematosus (SLE) stay in the focus of attention in recent decades due to significant influence of CNS lesions on SLE course in general, necessity to optimize therapeutic interventions and ...
M. I. Kaleda, I. P. Nikishina
doaj   +3 more sources

Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus [PDF]

Neurology Research International, 2018
Objective. Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by multisystem involvement, including the nervous system.
Mohammad-Amin Khajezadeh, Gholamreza Zamani, Bobak Moazzami, Zahra Nagahi, Mahdie Mousavi-Torshizi, Vahid Ziaee   +5 more
doaj   +3 more sources

The role of hsa_circ_0008945 in juvenile-onset systemic lupus erythematosus

BMC Medical Genomics, 2023
Background circular RNAs (circRNAs) play a crucial role in many physiological and pathological processes including juvenile-onset systemic lupus erythematosus (JSLE).
Qifan Wang, Baiye Xu, Qingmei Zhang, Haidao Wang, Shulian Chen, Tingting Chen, Shishan Liang   +6 more
doaj   +3 more sources

Systemic lupus erythematosus with juvenile onset: current status of the problem (literature review)

Современная ревматология
Patients with juvenile-onset systemic lupus erythematosus (jSLE) account for up to 25% of all SLE patients. The main difference between jSLE and SLE in adults is the greater role of genetic factors in the pathogenesis, higher activity, earlier ...
M. I. Kaleda, I.  P. Nikishina
doaj   +2 more sources

Elevated serum interferon-α2 associates with activity and flare risk in juvenile-onset systemic lupus erythematosus. [PDF]

Rheumatology (Oxford)
Objectives This study investigated serum IFN-α2 as a putative marker of disease activity and predictor of disease flares in juvenile systemic lupus erythematosus (jSLE).
Natoli V, Crow YJ, Hunt DPJ, Tharmaratnam K, Jorgensen AL, Beresford MW, Hedrich CM, Smith EMD.   +7 more
europepmc   +2 more sources