The role of neutrophil apoptosis in juvenile‐onset systemic lupus erythematosus [PDF]
Arthritis & Rheumatism, 2009 AbstractObjectiveAccumulation of apoptotic cells may lead to the development of systemic lupus erythematosus (SLE) through a breakdown in immune tolerance. Altered neutrophil apoptosis may contribute to nuclear autoantigen exposure, ultimately leading to autoantibody generation.
Angela, Midgley +4 more
openaire +2 more sources
Ocular changes due to the treatment of juvenile systemic lupus erythematosus [PDF]
, 2011 OBJECTIVE: To assess retrospectively the ocular changes in children and adolescents with juvenile systemic lupus erythematosus (JSLE) in a tertiary pediatric rheumatology service.
Finamor, Luciana Peixoto dos Santos +6 more
core +3 more sources
Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. [PDF]
, 2013 BackgroundJuvenile idiopathic arthritis is the most common rheumatic disease in children. Chronic uveitis is a common and serious comorbid condition of juvenile idiopathic arthritis, with insidious presentation and potential to cause blindness. Knowledge
Bauer-Mehren, Anna +5 more
core +3 more sources
Pediatric Rheumatology Online Journal, 2013 There were 54 patients with the juvenile onset of systemic lupus erythematosus included in the retrospective analysis, who were treated in the Institute of Rheumatology in Warsaw in the years 2002-2012. The average age of the onset of the illness in this
A. Gazda +8 more
semanticscholar +1 more source
The presence of high mobility group box-1 and soluble receptor for advanced glycation end-products in juvenile idiopathic arthritis and juvenile systemic lupus erythematosus [PDF]
, 2014 BACKGROUND: The involvement of high mobility group box-1 (HMGB1) in various inflammatory and autoimmune diseases has been documented but clinical trials on the contribution of this pro-inflammatory alarmin in children with juvenile idiopathic ...
Bobek, Dubravka +4 more
core +1 more source
New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]
, 1984 The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter +3 more
core +1 more source
Early-Onset Autoimmune Disease as a Manifestation of Primary Immunodeficiency [PDF]
, 2015 Autoimmune disorders (AID) have been increasingly observed in association with primary immunodeficiencies (PIDs). Here, we discuss the interface between PID and AID, focusing on autoimmune manifestations early in life, which can be diagnostic clues for ...
Carneiro-Sampaio, Magda +1 more
core +2 more sources
Lupus Science and Medicine, 2022 Objective Lupus nephritis is a key driver of morbidity and mortality in SLE. Detecting active nephritis on a background of pre-existing renal damage is difficult, leading to potential undertreatment and accumulating injury.
Michelle A Petri +10 more
doaj +1 more source
Evaluation of magnetic resonance imaging abnormalities in juvenile onset neuropsychiatric systemic lupus erythematosus. [PDF]
, 2016 The aim of this study was to describe the abnormalities identified with conventional MRI in children with neuropsychiatric systemic lupus erythematosus (NPSLE).
Al-Obaidi, M +8 more
core +1 more source
Pediatric Rheumatology Online Journal, 2011 Results At diagnosis the mean (SD) ages were 12.25(0.27) and 33.93(1.32) yrs, whereas the mean follow-up 6.63 (0.59) and 11.6 (0.7) yrs, for jSLE and aSLE respectively.
P. Nalbanti +10 more
semanticscholar +1 more source