Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus (jSLE) [PDF]
Molecular and Cellular Pediatrics, 2023 Systemic lupus erythematosus (SLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Approximately 15–20% of SLE patients develop the disease during childhood or adolescence (juvenile-onset SLE/jSLE).
Valentina Natoli +3 more
doaj +4 more sources
The role of hsa_circ_0008945 in juvenile-onset systemic lupus erythematosus [PDF]
BMC Medical Genomics, 2023 Background circular RNAs (circRNAs) play a crucial role in many physiological and pathological processes including juvenile-onset systemic lupus erythematosus (JSLE).
Qifan Wang +6 more
doaj +4 more sources
Vasculitis in Juvenile-Onset Systemic Lupus Erythematosus [PDF]
Frontiers in Pediatrics, 2019 Juvenile-onset systemic lupus erythematosus (JSLE) is a rare, heterogeneous multisystem autoimmune disease that can affect any organ, and present with diverse clinical and serological manifestations. Vasculitis can be a feature of JSLE.
Eve M. D. Smith +4 more
doaj +6 more sources
Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus [PDF]
Neurology Research International, 2018 Objective. Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by multisystem involvement, including the nervous system.
Mohammad-Amin Khajezadeh +5 more
doaj +5 more sources
Endocrine and metabolic comorbidities in juvenile-onset systemic lupus erythematosus [PDF]
Frontiers in MedicineBackground and aimsJuvenile-onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease affecting individuals under 18, causing multi-system impairment.
Su Jin Park +2 more
doaj +4 more sources
Autoantibody-based subgroups and longitudinal seroconversion in juvenile-onset systemic lupus erythematosus [PDF]
Lupus Science and Medicine, 2023 Objective To explore the clinical value of autoantibody-based subgroup framework and the trend of autoantibody fluctuation in juvenile-onset SLE (JSLE).Methods Eighty-seven patients with JSLE were retrospectively collected and divided into subgroups via ...
Zhen Yang +8 more
doaj +4 more sources
The role of assessment of renal biopsy in electron microscopy in making a diagnosis of juvenile-onset systemic lupus erythematosus in a 16-year-old female patient with depression and proteinuria – case report [PDF]
Central European Journal of Immunology, 2022 The course of juvenile-onset systemic lupus erythematosus may vary, from rapid multiorgan involvement to insidious development mimicking different medical conditions.
Tomasz Koszutski +4 more
doaj +2 more sources
Severe Juvenile-Onset Systemic Lupus Erythematosus: A Case Series-Based Review and Update [PDF]
Children, 2023 Juvenile-onset systemic lupus erythematosus (jSLE) is a multisystemic disease diagnosed in young patients based on the clinical criteria of the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
Sergi Huerta-Calpe +4 more
doaj +2 more sources
Case Report: Novel UNC93B1 variant causes rheumatoid arthritis and interstitial pneumonia [PDF]
Frontiers in ImmunologyBackgroundUNC93B1 is a transmembrane protein essential for regulating toll-like receptors (TLRs). Pathogenic variants in human UNC93B1 have recently been described in a limited number of patients with childhood systemic lupus erythematosus and chilblain ...
Tingyan He +6 more
doaj +2 more sources
Case Report: Diagnostic itinerary of a male case of juvenile-onset systemic lupus erythematosus in Bouake [PDF]
Frontiers in PediatricsJuvenile-onset systemic lupus erythematosus (JLES) is an autoimmune disease of unknown aetiology. It is more common in girls but can occur in boys. Its onset at an early age is more severe, causing potentially fatal damage if not treated early.
Aissata Doucoure Traore +15 more
doaj +2 more sources