Results 11 to 20 of about 346,856 (231)
Calcinosis in juvenile dermatomyositis: Updates on pathogenesis and treatment
Frontiers in Medicine, 2023 Calcinosis, or the deposition of insoluble calcium salts in the skin, subcutaneous tissue, fascia, tendons, and muscles, is a feared complication of juvenile dermatomyositis.
Caitlan S. Pinotti +4 more
doaj +2 more sources
Journal of Rheumatic Diseases, 2022 Juvenile dermatomyositis (JDM) is a systemic capillary vasculopathy. Patients present with proximal muscle weakness, raised muscle enzymes, and pathognomic skin rashes such as heliotrope rash, Gottron's papules. Main complications are calcinosis, lipodystrophy, osteoporosis. Complement-mediated damage of vessels is a major mechanism. Magnetic resonance
Jung-Woo Rhim
semanticscholar +5 more sources
SAGE Open Medical Case Reports, 2022 Juvenile dermatomyositis is a rare autoimmune myopathy of childhood, associated with systemic vasculopathy, primarily affecting the capillaries. Panniculitis is seen histologically in about 10% of patients with dermatomyositis; however, its clinical ...
Dylan C Ginter +5 more
doaj +2 more sources
Anasarca as the presenting symptom of juvenile dermatomyositis: a case series
Pediatric Rheumatology Online Journal, 2021 Background Juvenile Dermatomyositis (JDM) is an autoimmune disease that typically presents with classic skin rashes and proximal muscle weakness. Anasarca is a rare manifestation of this disease and is associated with a more severe and refractory course,
Emily E. Schildt, Deirdre De Ranieri
doaj +2 more sources
Arthritis Research & Therapy, 2023 Objectives Juvenile dermatomyositis (JDM) is a chronic autoimmune disease. Some patients remain in an active state even though they were administrated with a combination of corticosteroid and methotrexate.
Junmei Zhang +13 more
semanticscholar +1 more source
IEEE Transactions on Visualization and Computer Graphics, 2023 As the most common idiopathic inflammatory myopathy in children, juvenile dermatomyositis (JDM) is characterized by skin rashes and muscle weakness.
Kanglei Zhou +9 more
semanticscholar +1 more source
The von Willebrand Factor Antigen Reflects the Juvenile Dermatomyositis Disease Activity Score
Biomedicines, 2023 Objective: This study determined if an accessible, serologic indicator of vascular disease activity, the von Willebrand factor antigen (vWF:Ag), was useful to assess disease activity in children with juvenile dermatomyositis (JDM), a rare disease, but ...
Ellie Gibbs +4 more
semanticscholar +1 more source
Ugeskrift for Læger, 2023 Juvenile dermatomyositis (JDM) is a rare condition, which causes inflammation in children’s skin and musculoskeletal systems. Symptoms include characteristic skin rashes on the face and extremities, muscle pain and weakness. This is a case report of a ten-year-old boy initially suspected of having lupus erythematosus. He was later diagnosed with JDM by
Vigand Svendsen, Sebastian +3 more
openaire +2 more sources
Improvement in Disease Activity in Refractory Juvenile Dermatomyositis Following Abatacept Therapy
Arthritis & Rheumatology, 2023 This open‐label, 24‐week study was conducted to evaluate the safety and efficacy of abatacept in patients with refractory juvenile dermatomyositis (DM).
R. Curiel +10 more
semanticscholar +1 more source
B Cell Lymphocytosis in Juvenile Dermatomyositis
Diagnostics, 2023 In this study, we determined if B lymphocytosis may serve as a JDM biomarker for disease activity. Children with untreated JDM were divided into two groups based on age-adjusted B cell percentage (determined through flow cytometry): 90 JDM in the normal ...
Christopher Costin +7 more
semanticscholar +1 more source