Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage [PDF]
, 2017 To test the hypotheses that mutant huntingtin protein length and wild-type huntingtin dosage have important effects on disease-related transcriptional dysfunction, we compared the changes in mRNA in seven genetic mouse models of Huntington's disease (HD)
Albin, Roger +23 more
core
Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]
, 2013 Brown, Euan R. +2 more
core +1 more source
Book Review: Juvenile Huntington’s Disease and Other Trinucleotide Repeat Disorders [PDF]
, 2009 Alan Fryer
openalex +1 more source
Behavioral Genetics Research and Criminal DNA Databases [PDF]
, 2006 Kaye discusses DNA databanks and the potential use of such databanks for behavioral genetics research. He addresses the concern that DNA databanks serve as a limitless repository for future research and that the samples used in the databanks could be ...
Kaye, D. H.
core +2 more sources
Comorbidities and clinical outcomes in adult- and juvenile-onset Huntington’s disease: a study of linked Swedish National Registries (2002–2019) [PDF]
, 2022 Hannah Furby +7 more
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The MicrobeThe CRISPR-Cas systems, initially identified as bacterial defense mechanisms, have become innovative tools for genetic research and translational therapeutics. These systems are made up of clustered regularly interspaced short palindromic repeats (CRISPR)
Kamran Saeed +3 more
doaj
Juvenile-onset hypokinetic-rigid Huntington’s disease: a case with dual-tracer positron emission tomography [PDF]
, 2020 Xinyue Zhou +4 more
openalex +1 more source
Challenges & Strategies for Conducting Qualitative Research with Persons Diagnosed with Rare Movement Disorders [PDF]
, 2014 Unique features of Huntington’s disease and young-onset Parkinson’s disease, both neurodegenerative movement disorders, can pose challenges for conducting qualitative research.
LaDonna, Kori A., Ravenek, Michael J.
core +1 more source