Results 31 to 40 of about 1,564,693 (192)

Autoantibodies against complement C1q in systemic lupus erythemathosus [PDF]

, 2008
Complement and C1q, the first component of the classical pathway of activation of the complement system, are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), a systemic autoimmune disease.
Bigler, Cornelia
core   +1 more source

Genetic and epigenetic factors shape phenotypes and outcomes in systemic lupus erythematosus - focus on juvenile-onset systemic lupus erythematosus. [PDF]

Curr Opin Rheumatol
Purpose of review Systemic lupus erythematosus (SLE) is a severe autoimmune/inflammatory disease. Patients with juvenile disease-onset and those of non-European ancestry are most severely affected. While the exact pathophysiology remains unknown, common and rare gene variants in the context of environmental exposure and ...
Charras A, Hiraki LT, Lewandowski L, Hedrich CM.   +3 more
europepmc   +3 more sources

Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis [PDF]

, 2013
Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies.
Hartley, Louise, Court, Rachel, Cummins, E., Court, Rachel; id_orcid, Grove, Amy, Mohiuddin, Syed, Connock, Martin, Grove, Amy L., Sutcliffe, Paul, Kandala, Ngianga-Bakwin, Court, Rachel A., Kandala, Ngianga Bakwin, Cummins, Ewen, Connock, M., Sutcliffe, P. (Paul), Gordon, Caroline, Grove, Amy; id_orcid, Clarke, Aileen   +17 more
core   +1 more source

Phototesting and photoprotection in LE [PDF]

, 1997
Photosensitivity and induction of skin lesions following UV radiation is a common problem of patients with cutaneous and systemic forms of lupus erythematosus.
Kind, P., Walchner, M., Messer, G.
core   +1 more source

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis [PDF]

, 2013
Systemic sclerosis (SSc) is a fibrotic autoimmune disease in which the genetic component plays an important role. One of the strongest SSc association signals outside the human leukocyte antigen (HLA) region corresponds to interferon (IFN) regulatory ...
Schuerwegh, A. J., Alexander Kreuter (592), Herrick Ariane, Martín J., Carmona, F.D., Jacob M van Laar, Madelon C Vonk, Voskuyl AE, Denton C, Mónica Fernández-Castro, Martin Jose-Ezequiel, Hunzelmann Nicolas, Airó Paolo, Ariane Herrick (214049), Claudio Lunardi (12868), Paul Shiels (276244), Witte, T. de, Camps, M. T., Voskuyl Alexandre E., Distler, J.H., Riemekasten, Gabriela, H W Distler, Egurbide, María Victoria, Mónica Fernández-Castro (276238), Radstake TR, Camps, M.T., Egurbide, M. V., Simeón, C.P., Carreira, Patricia E., Airó, P., Kreuter, Alexander, Camps María Teresa, Airó, Paolo, Scorza, Raffaella, Martín, Javier, the Spanish Scleroderma Group, Nicolas Hunzelmann, Beltrán Emma, Madelon C. Vonk (213950), Torsten Witte, Javier Martín (2584444), Sáez-Comet, Luis, van Laar, J.M., María Teresa Camps, Callejas, J.L., Carmen Fonseca (214061), Airó P, Martin, J.E., Madhok, Rajan, Fernández Castro M, Kreuter, A., Herrick A, Carmen P. Simeón (5650816), Riemekasten Gabriela, Beltrán E, Radstake, T. R., Shiels, Paul G., Alexandre E. Voskuyl (213961), Carreira, P.E., Vonk, M.C., Lorenzo Beretta, Carreira PE, Hunzelmann N, Kreuter A, Patricia E. Carreira (276236), Beltrán, Emma, Carmona F. David, Rajan Madhok, Worthington J, Gabriela Riemekasten, Scorza R, Vonk MC, Simeón Carmen P., Witte, Torsten, Camps, María Teresa, Carmona FD, Herrick, A., Schuerwegh AJ, Paolo Airó, Distler, Jörg H W, Radstake Timothy R. D. J., Distler, J.H.W., Alexandre E Voskuyl, et al., José Luis Callejas (276237), Schuerwegh, Annemie J, Jane Worthington, Laar, Jacob M. van, Madhok R, Callejas, José Luis, Martín, J. E., Jacob M. van Laar (177818), Vonk Madelon C., Javier Martín, Beretta, Lorenzo, Emma Beltrá, Timothy R. D. J. Radstake (168224), Shiels Paul, Jörg H. W. Distler (3196062), Madhok Rajan, Callejas JL, Beltrán, E., Martin, Jose Ezequiel, Schuerwegh, A.J., Witte Torsten, Distler, J.H. W., Raffaella Scorza, Voskuyl, Alexandre E., Carmen P Simeón, Carmona, F David, Spanish Scleroderma, Claudio Lunardi, Rajan Madhok (23535), Group ", Voskuyl, A.E., Worthington, Jane, Egurbide, M.V., Jörg H W Distler, Saez-Comet, L., Callejas-Rubio, José Luis, Voskuyl, Alexandre E, van Laar JM, Simeón, Carmen P., Gabriela Riemekasten (276243), Denton, Christopher, Schuerwegh Annemie J., Camps MT, Paolo Airó (5650819), Witte T, Carmona, Francisco David, Denton, C., Lunardi, C., Fernández-Castro Mónica, Simeón, Carmen P, Riemekasten G, Luis Sáez-Comet (276239), Fonseca Carmen, Fernández-Castro, M., Herrick, Ariane, Timothy R D J Radstake, Scorza, R., Madhok, R., Denton Christopher, Fonseca, Carmen, Beretta L, Christopher Denton, Luis Sá Ez-Comet, Worthington, J., José Luis Callejas, Beretta, L., Annemie J Schuerwegh, Kreuter Alexander, Simeón CP, Nicolas Hunzelmann (213980), Lunardi Claudio, Jane Worthington (23502), Torsten Witte (32240), Emma Beltrán (276240), Lunardi, Claudio, Shiels, P., Carreira Patricia E., Fonseca C, Sáez Comet L, Shiels, Paul, Martín, J., Carmen Fonseca, F. David Carmona (276235), Riemekasten, G., Witte, T., Luis Sáez-Comet, Radstake, Timothy R. D. J., Jö Rg, van Laar, Jacob M., Egurbide María Victoria, Distler, Jörg H. W., Fernández-Castro, Monica, Radstake, T.R.D.J., van Laar Jacob M., Ariane Herrick, Emma Beltrán, Christopher Denton (276245), Alexander Kreuter, Martín Javier, Mó Nica Ferná Ndez-Castro, Shiels P, Vonk, Madelon C, Carreira, Patricia E, Fonseca, C., Paul Shiels, Callejas José Luis, Carmen P Simeó N, Martin JE, Lorenzo Beretta (214056), Egurbide MV, Distler Jörg H. W., Raffaella Scorza (214013), Vonk, Madelon C., María Victoria Egurbide, Hunzelmann, Nicolas, Carmona, F. David, Schuerwegh, Annemie J., Jose-Ezequiel Martin, Beretta Lorenzo, Distler, J. H., Patricia E Carreira, María Teresa Camps (276241), Scorza Raffaella, Annemie J. Schuerwegh (213966), Sáez-Comet Luis, F David Carmona, María Victoria Egurbide (276242), Laar, J.M. van, Hunzelmann, N., Worthington Jane, Martin, Jose-Ezequiel, van Laar, Jacob M, Spanish Scleroderma Group, Jose-Ezequiel Martin (213926), Distler JH, Radstake, Timothy R D J   +219 more
core   +2 more sources

The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland [PDF]

, 2014
OBJECTIVES: To describe disease characteristics and treatment modalities in a multidisciplinary cohort of systemic lupus erythematosus (SLE) patients in Switzerland.
Stoll, T., Cohen, Clemens, Chizzolini, Carlo, Swiss Systemic Lupus Erythematosus Cohort Study Group, Hunziker, Thomas, Hauser, T., Clemens Cohen, Von Kempis, J., Stoll, Thomas, Katrin Koenig, Gayet-Ageron, Angèle, Carlo Chizzolini, Dayer, E., Koenig, K., Hunziker, T., Gregor Lindner, Chizzolini, C., François Spertini, Trendelenburg, M., Leimgruber, A., Lindner, Gregor, Ribi, C., Von Kempis, Johannes, Thomas Hauser, Eric Dayer, Annette Leimgruber, Petra Otto, Dayer, Eric, Koenig, Katrin, Cohen, C., Leimgruber, Annette, Spertini, F., Hauser, Thomas, Eisenberger, Ute, Thomas Stoll, Lindner, G., Otto, P., Ribi, Camillo, Eisenberger, U., Ute Eisenberger, Thomas Hunziker, Marten Trendelenburg, Johannes Von Kempis, Trendelenburg, Marten, Otto, Petra, Camillo Ribi, Spertini, François, Gayet-Ageron, A., Angèle Gayet-Ageron   +48 more
core   +1 more source

Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature. [PDF]

Am J Clin Dermatol, 2017
Oral ulcers are the most common mucosal sign in juvenile-onset systemic lupus erythematosus (JSLE). The ulcers are one of the key clinical features; however, the terminology of oral ulcers, especially in JSLE patients, is often vague and ill-defined. In fact, there are several clinical manifestations of oral ulcers in JSLE, and some lesions occur when ...
Rodsaward P, Prueksrisakul T, Deekajorndech T, Edwards SW, Beresford MW, Chiewchengchol D.   +5 more
europepmc   +4 more sources

ICF Core Sets: how to specify impairment and function in systemic lupus erythematosus [PDF]

, 2006
The World Health Organization’s International Classification of Function (ICF) is a tool to characterize and illuminate better the full of array of problems a patient faces when affected by disease.
Pisetsky, D.S., Stucki, Gerold, Cieza, A., Yarboro, C.H., Stamm, T.A., Aringer, M., Smolen, J.S., Stucki, G.   +7 more
core   +1 more source

Juvenile and juvenile-onset systemic lupus erythematosus patients: Clinical characteristics, disease activity and damage

Egyptian Pediatric Association Gazette, 2017
Background: The diagnosis of systemic lupus erythematosus (SLE) in children is challenging. The heterogeneous manifestations and disease impact on the child’s growth highlight the importance of timely diagnosis and management.
Rasha E. Gheith, Iman I. El-Gazzar, Hussein S. El Fishawy, Abeer M. Nour El-Din, Dina M.R. Bahgat, Tamer A. Gheita   +5 more
doaj   +1 more source

The V_H gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus [PDF]

, 2003
In systemic lupus erythematosus (SLE) it has been hypothesized that self-reactive B cells arise from virgin B cells that express low-affinity, nonpathogenic germline V genes that are cross-reactive for self and microbial antigens, which convert to high ...
Stott, DI, Gary Rowley, Fraser, N.L.W., Field, M, Fraser, NLW, Rowley, G., Field, M., Max Field, Rowley, G, David I Stott, Stott, D.I., Nicola LW Fraser   +11 more
core   +1 more source