Results 41 to 50 of about 1,564,693 (192)

Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature. [PDF]

Pediatr Rheumatol Online J, 2015
Patients diagnosed with juvenile-onset systemic lupus erythematosus (JSLE) often have skin and oral lesions as part of their presentation. These mucocutaneous lesions, as defined by the American College of Rheumatology (ACR) in 1997, include malar rash, discoid rash, photosensitivity and oral ulcers. It is therefore essential to recognize mucocutaneous
Chiewchengchol D, Murphy R, Edwards SW, Beresford MW.   +3 more
europepmc   +4 more sources

Bone mineral density in juvenile onset Systemic lupus erythematosus

Indian Pediatrics, 2015
To compare bone mineral density in patients with juvenile-onset Systemic lupus erythematosus and healthy controls.Serial bone mineral density measurements in 27 patients with juvenile-onset systemic lupus were compared to 97 healthy age-matched controls.All patients with juvenile-onset had low bone mineral density scores at initial assessment that ...
R, Abdwani, E, Abdulla, S, Yaroubi, H, Bererhi, I, Al-Zakwani   +4 more
openaire   +2 more sources

Exercise as adjunctive therapy for systemic lupus erythematosus [PDF]

, 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the safety and effectiveness of structured exercise interventions for adults with systemic lupus ...
Greene, David, Cameron, Melainie, O'Neill, Sean, Frade, Stephanie   +3 more
core   +1 more source

Case Report: Novel UNC93B1 variant causes rheumatoid arthritis and interstitial pneumonia

Frontiers in Immunology
BackgroundUNC93B1 is a transmembrane protein essential for regulating toll-like receptors (TLRs). Pathogenic variants in human UNC93B1 have recently been described in a limited number of patients with childhood systemic lupus erythematosus and chilblain ...
Tingyan He, Junbin Ou, Lijuan Huang, Xinyi Zhou, Linlin Wang, Xiaolin Li, Jun Yang   +6 more
doaj   +1 more source

Off-label use of tocilizumab to treat non-juvenile idiopathic arthritis in pediatric rheumatic patients: a literature review

Pediatric Rheumatology Online Journal, 2018
Tocilizumab, an anti-interleukin-6 (IL-6) agent, is indicated as a treatment for several autoimmune or inflammatory diseases, including rheumatoid arthritis and juvenile idiopathic arthritis (JIA). IL-6 plays roles in both immune system dysregulation and
Ju-Yang Jung, Moon-Young Kim, Chang-Hee Suh, Hyoun-Ah Kim   +3 more
doaj   +1 more source

Association of rs7574865 G/T polymorphism of STAT4 gene with juvenile onset of systemic lupus erythematosus

Современная ревматология, 2022
Systemic lupus erythematosus (SLE) with juvenile onset (jSLE) is a complex autoimmune disease involving many organs and systems. The single nucleotide polymorphism rs7574865 of the STAT4 (signal switch and transcription activator 4) gene is associated ...
M. Yu. Krylov, M. I. Kaleda, I. A. Guseva, N. V. Konovalova, D. A. Varlamov   +4 more
doaj   +1 more source

FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans. [PDF]

, 2011
OBJECTIVES: To evaluate FCGR3B copy number variation (CNV) in African and European populations and to determine if FCGR3B copy number is associated with SLE and SLE nephritis risk in Afro-Caribbeans, adjusting for African genetic ancestry.
A. L. Patrick, Molokhia, Mariam, Vyse, Tim J, A. L. Roberts, M. Molokhia, McKeigue, Paul; id_orcid, T. J. Vyse, Roberts, Amy L., E. Petretto, Patrick, Alan Leslie, Aitman, Tim J, McKeigue, Paul, Aitman, Tim, M. Fanciulli, P. McKeigue, Roberts, Amy, Vyse, Tim J., Aitman, Tim J., Petretto, Enrico, T. J. Aitman, Fanciulli, Manuela, Roberts, Amy L   +21 more
core   +1 more source

Association between academic performance and cognitive dysfunction in patients with juvenile systemic lupus erythematosus

Revista Brasileira de Reumatologia, 2016
Objective To determine whether there is an association between the profile of cognitive dysfunction and academic outcomes in patients with juvenile systemic lupus erythematosus (JSLE).
Renan Bazuco Frittoli, Karina de Oliveira Peliçari, Bruna Siqueira Bellini, Roberto Marini, Paula Teixeira Fernandes, Simone Appenzeller   +5 more
doaj   +1 more source

Systemic lupus erythematosus organ manifestation and disease activity in children based on Mexican systemic lupus erythematosus disease activity index score at East Java, Indonesia

Indian Journal of Rheumatology, 2021
Background: Disease activity in systemic lupus erythematosus (SLE) is associated with organ damage, outcome worsening, comorbidities, and mortalities in the patients.
Zahrah Hikmah, Anang Endaryanto, I Dewa Gede Ugrasena   +2 more
doaj   +1 more source

Exome Sequencing Uncovers Phenotypic and Genotypic Heterogeneity in 196 Indian Families Evaluated for Autoinflammatory Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autoinflammatory disorders (AIDs) are a clinically heterogeneous group of inborn errors of immunity primarily caused by dysregulation in the innate immune system. Clinical diagnosis is often challenging due to clinical heterogeneity and the overlapping phenotypes with other inborn errors of immunity and monogenic conditions that mimic AIDs ...
Vaishnavi Ashok Badiger, Periyasamy Radhakrishnan, Suma Balan, Anand P. Rao, Prajna Udupa, Karthik Vijay Nair, Bhagesh Hunakunti, Adarsh Pooradan Prasannakumar, Sanket Limaye, Huzail Gani Shaikh, Rohit Naik, Mahesh Janarthanan, Sudharshan Sridharan, Vishal Sondhi, Sheela Nampoothiri, Hitesh Shah, Sabrinath Mahadevan, Mahabaleshwar Mamadapur, Devang Pandya, Katta Mohan Girisha, Abhay Shivpuri, Amita Moirangthem, Jyothi Raghuram, Gandham Sri Lakshmi Bhavani, Sachin Jeevanagi, Girish Subramaniam, Amita Aggarwal, Anju Shukla, Dhanya Lakshmi Narayanan   +28 more
wiley   +1 more source