Results 231 to 240 of about 4,454,791 (262)

Expression of C antigen in transduced K562 cells

Transfusion, 2001
BACKGROUND: The Rh blood group system is involved in HDN and transfusion reactions. A retrovirus‐expression system was previously used to show that polypeptides carrying the Rh blood group antigens are encoded by the RHD and RHCE genes. This study investigated the structure of the C antigen.STUDY DESIGN AND METHODS: K562 cells were transduced with full‐
J S, Smythe, D J, Anstee
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Photodynamic Action of Benzo[a]pyrene in K562 Cells

Photochemistry and Photobiology, 2007
AbstractBenzo[a]pyrene (BaP) is ubiquitously distributed in the environment, being considered the most phototoxic element among polycyclic aromatic hydrocarbon (PAHs). In presence of oxygen, PAHs can act as a photosensitizer by means of promoting photo‐oxidation of biological molecules (photodynamic action, PDA).
Daza de Moraes Vaz Batista, Filgueira, Diana Paula, Salomão de Freitas, Ana Paula, de Souza Votto, Gilberto, Fillmann, José Maria, Monserrat, Laura Alicia, Geracitano, Gilma, Santos Trindade   +6 more
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The exosome pathway in K562 cells is regulated by Rab11

Journal of Cell Science, 2002
During maturation, reticulocytes lose some membrane proteins that are not required on the mature red cell surface. The proteins are released into the extracellular medium associated with vesicles that are formed by budding of the endosomal membrane into the lumen of the compartment; this process results in the formation of multivesicular bodies (MVBs).
Ariel, Savina, Michel, Vidal, Maria I, Colombo   +2 more
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Mechanism of Simvastatin-Induced K562 Cell Apoptosis

Pharmacology, 2009
Statins are being widely used for the therapy and prevention of several types of tumors, including human chronic myelogenous leukemia, but the underlying molecular mechanisms still remain unknown. Therefore, inhibition of cell proliferation, apoptosis and involved molecules were investigated in K562 cells after incubation with simvastatin.The results ...
Yong-Chang, Yang, Dai-Wen, Xiao, Hua, Liu, Liang-Min, Chuan, Ya-Li, Zeng, Ding-An, Zhou, Wen, Liu, Guo-Qiang, Xu, Wen-Fang, Huang   +8 more
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[Knock-down of CARMA1 in K562 cells inhibits the invasion and metastasis of K562 cells].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2014
To study the effects of caspase recruitment domain membrane-associated guanylate kinase protein 1 (CARMA1) knock-down using RNAi technology on cell proliferation, colony forming, invasion and metastasis of the K562 cells.K562 cells with stably-silenced CARMA1 gene was constructed by lentivirus-mediated RNAi technology.
Fang, Liu, Lingyan, Wang, Jieyu, Li, Shuping, Chen, Yunbin, Ye   +4 more
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Persistent infection of K562 cells by encephalomyocarditis virus

Journal of Virology, 1990
Infection of human erythroleukemic K562 cells by encephalomyocarditis virus readily resulted in establishment of persistently infected cultures. In contrast to the usual typical lytic infection by encephalomyocarditis virus, in which trypan blue staining of cells reaches close to 100% by about 15 h postinfection, K562 cell cultures required 3 to 4 days
I U, Pardoe, K K, Grewal, M P, Baldeh, J, Hamid, A T, Burness   +4 more
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A kinetic and clonal analysis of heterogeneity in K562 cells

Journal of Cellular Physiology, 1984
AbstractExpression of markers of differentiation was measured in a clone of the continuous cell line K562, derived originally from the cells of a patient with leukemia. Three of the markers were lineage specific, R18 for erythropoiesis and 80H.5 and My‐1 for granulopoiesis. The fourth marker was the self‐renewal capacity of clonogenic cells.
S, Alder, A, Ciampi, E A, McCulloch
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Reduction of extracellular dehydroascorbic acid by K562 cells

Cell Biochemistry and Function, 1996
AbstractK562 erythroleukaemic cells produced ascorbate when incubated with dehydroascorbic acid. The reduction depended on the number of cells and on the concentration of dehydroascorbic acid. The observed rate consists of a high affinity (apparent) Km 7 μM, Vmax 3·25 pmol min−1 (106 cells)−1 and a low affinity component, which was non‐saturable up to ...
E, Schweinzer, Y, Mao, P, Krajnik, N, Getoff, H, Goldenberg   +4 more
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[Analysis of methylation status of the promoter of mdr1 gene in K562 and K562/DNR cells].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2008
To analyze the methylation patterns of mdr1 gene promotor in both K562 cell and K562/DNR cells and the relationship between promotor methylation and P-gp expression.mdr1 gene expression was analyzed by flow cytometry and RT-PCR, methylation status of the promotor of mdr1 gene by bisulfite-sequencing (including two GC-box).mdr1 gene was found methylated
Feng, Gao, Jing-dong, Zhang, Yun-peng, Liu, Xiang-lan, Lu   +3 more
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[Screening for drug resistance related microRNAs in K562 and K562/A02 cell lines].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016
To explore the relationship between microRNA and drug resistance in leukemia treatment by screening and identifying the microRNAs which differentially express in K562 cell line and its adriamycin resistant cells-K562/A02 cell line.The drug resistance potency of K562/A02 cells was evaluated by MTT assay.
Yi-Xiong, Cao, Chong-Wen, Dai, Guang-Sen, Zhang   +2 more
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