Results 11 to 20 of about 33,316 (150)

Kaempferol promotes osteogenic differentiation of mouse bone marrow mesenchymal cells under tension stress via the mTORC1 signaling pathway

口腔疾病防治, 2021
Objective To investigate the activation of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway molecules during the process by which kaempferol (Kae) promotes osteogenic differentiation of mouse bone marrow mesenchymal cells (BMMCs ...
CUI Linna, JIANG Xiaowen, HUANG Huaqing, CHEN Jinyong   +3 more
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The Effect of Kaempferol on Autophagy and Nrf-2 Signaling in a Rat Model of Aβ1-42-induced Alzheimer’s Disease

Caspian Journal of Neurological Sciences, 2022
Background: Numerous pieces of evidence support that oxidative stress is a key factor in the pathogenesis of neurodegenerative diseases, like Alzheimer’s Disease (AD).
Samira Rashtiani, Kambiz Rohampour, Parvin Babaei, Adeleh Jafari   +3 more
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Kaempferol: A Key Emphasis to Its Anticancer Potential

Molecules, 2019
A marked decrease in human cancers, including breast cancer, bone cancer, and cervical cancer, has been linked to the consumption of vegetable and fruit, and the corresponding chemoprotective effect has been associated with the presence of several active
Muhammad Imran, Bahare Salehi, Javad Sharifi-Rad, Tanweer Aslam Gondal, Farhan Saeed, Ali Imran, Muhammad Shahbaz, Patrick Valere Tsouh Fokou, Muhammad Umair Arshad, Haroon Khan, Susana G. Guerreiro, Natália Martins, Leticia M. Estevinho   +12 more
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Enhanced Flavonoid Accumulation Reduces Combined Salt and Heat Stress Through Regulation of Transcriptional and Hormonal Mechanisms

Frontiers in Plant Science, 2021
Abiotic stresses, such as salt and heat stress, coexist in some regions of the world and can have a significant impact on agricultural plant biomass and production. Rice is a valuable crop that is susceptible to salt and high temperatures.
Rahmatullah Jan, Rahmatullah Jan, Nari Kim, Seo-Ho Lee, Muhammad Aaqil Khan, Sajjad Asaf, Lubna, Jae-Ryoung Park, Saleem Asif, In-Jung Lee, Kyung-Min Kim, Kyung-Min Kim   +11 more
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Kaempferol Promotes Apoptosis While Inhibiting Cell Proliferation via Androgen-Dependent Pathway and Suppressing Vasculogenic Mimicry and Invasion in Prostate Cancer

Analytical Cellular Pathology, 2019
Kaempferol is a well-known natural flavonol reported to be a potential treatment for multiple cancers. In this study, we demonstrated that cell growth of androgen-sensitive LNCaP cells could be inhibited 33% by 5 μM kaempferol, around 60% by 10 μM ...
Jun Da, Mingxi Xu, Yiwei Wang, Wenfeng Li, Mujun Lu, Zhong Wang   +5 more
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Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways

Frontiers in Pharmacology, 2021
Kaempferol has been reported to exhibit beneficial effect on the osteogenic differentiation in mesenchymal stem cells (MSC) and osteoblasts. In our previous study, dexamethasone (DEX) demonstrated inhibitory effect on MC3T3-E1 cells differentiation.
Baocheng Xie, Baocheng Xie, Zhanwei Zeng, Zhanwei Zeng, Shiyi Liao, Shiyi Liao, Chenhui Zhou, Longhuo Wu, Daohua Xu, Daohua Xu   +9 more
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Regulatory mechanisms of kaempferol on iNOS expression in RINm5F β-cells under exposure to interleukin-1β

Heliyon, 2023
Proinflammatory cytokines and NO play crucial roles in islet β-cells dysfunction. Though anti-inflammatory effects of kaempferol were revealed in several studies, the detailed mechanisms remain unclear.
Seo-Yoon Chang, Yongjun Ko, Myung-Jun Kim   +2 more
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Kaempferol Improves Lung Ischemia-Reperfusion Injury via Antiinflammation and Antioxidative Stress Regulated by SIRT1/HMGB1/NF-κB Axis

Frontiers in Pharmacology, 2020
Trauma, organ transplantation, and thromboembolism are the main causes of lung ischemia-reperfusion injury (LIRI), and new therapies and drugs are urgent to relieve LIRI. In preliminary experiment, authors found that kaempferol could improve LIRI in rats,
Chunli Yang, Wenkai Yang, Zhaohui He, Huiwei He, Xiaogang Yang, Yuanhua Lu, Hongbo Li   +6 more
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Physico-chemical and spectroscopic investigation of flavonoid dispersed CnTAB micelles

Royal Society Open Science, 2022
In this study, kaempferol (0.2 m/mmol kg−1) dispersed cationic surfactant micelles were prepared as a function of alkyltrimethylammonium bromide (CnTAB) hydrophobicity (C = 12 to C = 16).
Dileep Kumar, K. M. Sachin, Naveen Kumari, Ajaya Bhattarai   +3 more
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Kaempferol and Kaempferol Rhamnosides with Depigmenting and Anti-Inflammatory Properties

Molecules, 2011
The objective of this study was to examine the biological activity of kaempferol and its rhamnosides. We isolated kaempferol (1), a-rhamnoisorobin (2), afzelin (3), and kaempferitrin (4) as pure compounds by far-infrared (FIR) irradiation of kenaf ...
Jae Youl Cho, Dong Ha Cho, Keun Ha Lee, Sun Sang Kwon, Dae Sung Yoo, Soo Mi Ahn, Amal Kumar Ghimeray, Ho Sik Rho   +7 more
doaj   +1 more source