Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Polygonum cognatum extracts exhibit strong antioxidant, anti‐inflammatory, antidiabetic, and antimicrobial activities. This study demonstrates, for the first time, histone deacetylase inhibitory activity, revealing epigenetic modulation potential.
Serhat Karaman +2 more
wiley +1 more source
Investigating the therapeutic mechanism of Asarum for oral ulcer from a network pharmacology perspective. [PDF]
Zhu X, Zhao M, Zhu H, Wang Y, Lu Y.
europepmc +1 more source
Biological Flora of Britain and Ireland: Geranium sylvaticum*
Geranium sylvaticum is a perennial forb of upland grasslands, woodlands and riverbanks in northern Britain, with scattered native occurrences also in Wales, central England and Northern Ireland. It has an extensive native range in Europe and Asia. The species is gynodioecious, with individual plants typically female or hermaphrodite.
Markus Wagner +6 more
wiley +1 more source
Exploring the potential mechanisms of anti-pulmonary fibrosis effects of Luo Han Guo via network pharmacology, molecular docking, and experimental validation. [PDF]
Cui Q +11 more
europepmc +1 more source
Lipid-Lowering Potential of Almond Hulls (Quercetin, Baicalein, and Kaempferol): Insights from Network Pharmacology and Molecular Dynamics [PDF]
Qiming Miao +8 more
openalex +1 more source
Light regulates tomato fruit metabolome via SlDML2‐mediated global DNA demethylation
In tomato growth and development, red and blue light signals are captured by the photoreceptors phyB2 and CRY1a, which kickstart tomato fruit ripening by activating HY5, which activates DNA demethylation via DML2 to trigger a metabolic and ripening transformation cascade within the tomato.
Zixin Zhang +15 more
wiley +1 more source
Innovative screening for mutants affected in seed oil/protein allocation identifies TRANSPARENT TESTA7 as a regulator of oil accumulation. [PDF]
Lécureuil A +7 more
europepmc +1 more source

