Results 91 to 100 of about 237,530 (303)

Some Inequalities About the Kaplan-Meier Estimator

open access: yesThe Annals of Statistics, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A comparative retrospective longitudinal study of arthritis risk and cognitive decline in older adults

open access: yesScientific Reports
Arthritis often results in unmet healthcare needs for older adults with cognitive decline, who may struggle to communicate pain or recall symptoms. However, the risk factors for arthritis in this group remain underexplored.
Jennifer Ivy Kim, Bada Kang
doaj   +1 more source

Long⁃term prognosis of endovascular treatment in patients with acute ischemic stroke due to large vessel occlusion presenting beyond the conventional time window

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To evaluate the long⁃term prognosis in patients with acute ischemic stroke due to large vessel occlusion presenting beyond the conventional time window (> 24 h) who received endovascular treatment (EVT) combined with best medical treatment (BMT)
LIU Shu⁃ling   +5 more
doaj   +1 more source

Retention on antiretroviral therapy in low- and middle-income countries: systematic review of papers and abstracts since 2008 [PDF]

open access: yes, 2013
This repository item contains a single issue of the Health and Development Discussion Papers, an informal working paper series that began publishing in 2002 by the Boston University Center for Global Health and Development.
Fox, Matthew, Rosen, Sydney
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Using weibull mixture distributions to model heterogeneous survival data [PDF]

open access: yes, 2003
In this article we use Bayesian methods to fit a Weibull mixture model with an unknown number of components to possibly right censored survival data. This is done using the recently developed, birth-death MCMC algorithm.
Marín Díazaraque, Juan Miguel   +2 more
core   +1 more source

Bootstrapping the Kaplan–Meier estimator on the whole line [PDF]

open access: yesAnnals of the Institute of Statistical Mathematics, 2018
This article is concerned with proving the consistency of Efron's (1981) bootstrap for the Kaplan-Meier estimator on the whole support of a survival function. While other works address the asymptotic Gaussianity of the estimator itself without restricting time (e.g.
openaire   +3 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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