Results 91 to 100 of about 2,137,881 (310)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

SURVIVAL ANALYSIS OF CANCER PATIENTS USING PARAMETRIC AND NON-PARAMETRIC APPROACHES [PDF]

Pakistan Veterinary Journal, 2007
Exploring the health related quality of life is usually the focus of the survival studies. Using the health data of cancer registry in Multan, Pakistan, an investigation about the survival pattern of cancer patients was explored, using the non-parametric
M. AKRAM, M. AMAN ULLAH AND R. TAJ
doaj  

Cox proportion hazard model for patients with hepatitis disease in Iraq

مجلة بغداد للعلوم, 2009
Cox regression model have been used to estimate proportion hazard model for patients with hepatitis disease recorded in Gastrointestinal and Hepatic diseases Hospital in Iraq for (2002 -2005).
Baghdad Science Journal
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Serum iron is associated with the prognosis in sepsis based on a large-scale database

BMC Infectious Diseases
Background Studies on serum iron levels and prognosis in sepsis are limited. We conducted retrospective research based on a public database to investigate the relationships between the serum iron levels and clinical outcomes in sepsis.
Ju Luo, Ning Ding
doaj   +1 more source

Kaplan-Meier estimate of percentage of cardiovascular mortality.

, 2014
Kaplan-Meier estimate of percentage of cardiovascular mortality.
Yuen-Kwun Wong (521825), Kay-Cheong Teo (521826), Richard Shek-Kwan Chang (521827), Sonny Fong-Kwong Hon (521828), Shu-Leong Ho (101984), Raymond Tak-Fai Cheung (521829), Koon-Ho Chan (291734), Hung-Fat Tse (351982), Kui-Kai Lau (521824), Leonard Sheung-Wai Li (521830), Chung-Wah Siu (351983)   +10 more
core   +1 more source

Kaplan-Meier estimate curves for time to return after being more than 28 days late for ART refill by intervention status.

, 2022
Kaplan-Meier estimate curves for time to return after being more than 28 days late for ART refill by intervention status.
Nancy Padian (269907), Mpande Mukumbwa-Mwenechanya (9073164), Monika Roy (2227576), Izukanji Sikazwe (531945), Chanda Mwamba (4962199), Ingrid Eshun-Wilson (4763313), Charles B. Holmes (7571867), David W. Dowdy (8964830), Carolyn Bolton Moore (8836946), Hojoon Sohn (197306), Elvin H. Geng (7456184), Jake M. Pry (5340818), Stephanie Topp (3930335)   +12 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Is There a Two-Way Risk between Decreased Testosterone Levels and the Progression and Prognosis of Chronic Kidney Disease? A Cohort Study Based on the National Health and Nutrition Examination Survey Database

The World Journal of Men's Health
Purpose: The causal relationship between the incidence and prognosis of chronic kidney disease (CKD) and serum testosterone levels in patients is not yet fully understood.
Jiashan Pan, Zhenming Zheng, Xike Mao, Dekai Hu, Wenbo Wang, Guiyi Liao, Zongyao Hao   +6 more
doaj   +1 more source

Immunobiological Therapy in Moderate-to-Severe Psoriasis: A Retrospective Cohort Study Investigating the Effects of Inadequate Therapeutic Compliance on Drug Survival

Dermatology and Therapy
Introduction Evaluating psoriasis care in Brazil, a country characterized by its vast geographical expanse, may provide valuable lessons for healthcare systems globally.
Luciana A. Ribeiro, Patrícia S. Kurizky, Rodrigo R. de Sena, Samia Fares, Gabriel B. F. dos Santos, Letícia O. Galvão, Licia Maria H. da Mota, Ciro M. Gomes   +7 more
doaj   +1 more source