Kaposi's sarcoma-associated herpesvirus at 27 [PDF]
Tumour Virus Research, 2021 Kaposi's sarcoma-associated herpesvirus (KSHV) was discovered 27 years ago and its link to several pathologies – Kaposi's sarcoma, primary effusion lymphoma, and the B cell variant of Multicentric Castleman disease – is now well established.
Marta Maria Gaglia
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Toward Anti-Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen. [PDF]
ChemMedChemIt is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Berwanger A +10 more
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Hypoxic reactivation of Kaposi's sarcoma associated herpesvirus [PDF]
Cell InsightHypoxic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) refers to the phenomenon under low oxygen where the virus goes from latent to lytic replication.
Rajnish Kumar Singh +2 more
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Kaposi’s Sarcoma-associated Herpesvirus
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016 Background: Kaposi’s sarcoma (KS) revealed by Moritz Kaposi first time in 1872. In the early 1980, the prevalence of SK began to increase dramatically.
Novia Indriyani Adisty +2 more
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Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis [PDF]
mBio, 2018 Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi’s sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Hye-Ra Lee +8 more
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Frontiers in Cell and Developmental Biology, 2023 Kaposi’s sarcoma associated herpesvirus (KSHV) is causative agent of Kaposi’s sarcoma, Multicentric Castleman Disease and Pleural effusion lymphoma. KSHV-encoded ORF17 encodes a protease which cleaves -Ala-Ala-, -Ala-Ser- or -Ala-Thr-bonds.
Misbahuddin M Rafeeq +12 more
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Mycosis fungoides and Kaposi’s sarcoma association in an HIV-negative patient [PDF]
Anais Brasileiros de Dermatologia, 2016 The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides ...
Maria Carolina Prado Fleury Bariani +4 more
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Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy
Clinical Case Reports, 2022 Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona +6 more
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Pulmonary Kaposi's sarcoma—an atypical clinical presentation
International Journal of Infectious Diseases, 2022 HIV-associated Kaposi's sarcoma is an angioproliferative neoplasia caused by infection with human herpesvirus 8. It typically presents with mucocutaneous involvement. Pulmonary Kaposi's sarcoma is rare, and an uncommon form of initial presentation of the
Ana Luísa Ramos +4 more
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Elevated iNOS and 3′-nitrotyrosine in Kaposi's Sarcoma tumors and mouse model
Tumour Virus Research, 2023 Kaposi's Sarcoma (KS) is a heterogenous, multifocal vascular malignancy caused by the human herpesvirus 8 (HHV8), also known as Kaposi's Sarcoma-Associated Herpesvirus (KSHV). Here, we show that KS lesions express iNOS/NOS2 broadly throughout KS lesions,
Olga Vladimirova +8 more
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