Results 31 to 40 of about 14,230 (249)

Molecular biology of Kaposi's sarcoma-associated herpesvirus [PDF]

Frontiers in Bioscience, 2002
Over the past twenty odd years, kaposi's sarcoma has launched from being a rare pathological curiosity to a significant public health concern. This massive increase in incidence, concurrent with the aids epidemic, has sparked a tremendous amount of interest in uncovering the etiopathogenesis of this disease.
A. Cotter Murray
openalex   +3 more sources

Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4 [PDF]

, 2017
Members of the herpesviral family use multiple strategies to hijack infected host cells and exploit cellular signaling for their pathogenesis and latent infection.
Aigerim, A, Cha, J.S, Cho, H.-S, Cho, N.-H., Choi, M.-S, Han, S.K, Kim, H, Kim, K, Kim, S, Kim, Y, Kwon, E.-K, Lee, J.-W, Min, C.-K, Nam, H.-J, Schmidt, S   +14 more
core   +1 more source

Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]

F1000Research, 2016
Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic human herpesvirus. KSHV is associated with three cancers in the human population: KS, primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). KS is the leading cause
Nathan J. Dissinger, Blossom Damania
doaj   +1 more source

Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections

Nature Communications, 2020
Disease prognosis after infection with Kaposi’s sarcoma-associated herpesvirus and Epstein-Barr Virus is highly variable. Here the authors carry out epidemiological and genetic analysis of a Ugandan cohort and suggest complex interactions may influence ...
Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Deepti Gurdasani, Martin O. Pollard, Alexander T. Dilthey, Alexander J. Mentzer, Vickie Marshall, Elena M. Cornejo Castro, Cristina Pomilla, Elizabeth H. Young, Gershim Asiki, Martin L. Hibberd, Manjinder Sandhu, Paul Kellam, Robert Newton, Denise Whitby, Inês Barroso   +19 more
doaj   +1 more source

Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma Tissues. [PDF]

PLoS Pathogens, 2017
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically related to Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD).
Rui Sun, Xiaohua Tan, Xing Wang, Xiaodong Wang, Lei Yang, Erle S Robertson, Ke Lan   +6 more
doaj   +1 more source

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Baquero-Perez, B, Berndt, A, Hughes, DJ, Jackson, BR, Owen, CB, Schumann, S, Whitehouse, A   +6 more
core   +1 more source

Restricted Kaposi’s Sarcoma (KS) Herpesvirus Transcription in KS Lesions from Patients on Successful Antiretroviral Therapy

mBio, 2011
Kaposi’s sarcoma (KS) is caused by Kaposi’s sarcoma-associated herpesvirus (KSHV; human herpesvirus 8). KS is an AIDS-defining cancer, and it is changing in the post-antiretroviral therapy (post-ART) era.
Dirk P. Dittmer
doaj   +1 more source

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. [PDF]

PLoS ONE, 2014
Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed
Brittany M Ashlock, Qi Ma, Biju Issac, Enrique A Mesri   +3 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]

, 2013
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad, B. Tolani, Ballon, Benhamou, Bower, Bren, C. Graham, Chang, Chaudhary, Chugh, Delmore, Dong, Du, Dupin, Dupin, Eeva, Eeva, Field, Gerondakis, Guasparri, H. Matta, H. Yi, Hassman, Herzog, Lee, Liu, Madureira, Matta, Matta, Matta, Matta, Mineva, Nador, Niiro, P. M. Chaudhary, Parravicini, Punj, Schauer, Soulier, Sun, Sun, Sun, Thome, Vrzalikova, Waterston, Wu, Wu, Wu, Y. Suo, Y. Yang, Yang, Yang, Young, Zhao   +53 more
core   +1 more source

Epigenetic diversity of Kaposi’s sarcoma–associated herpesvirus [PDF]

Nucleic Acids Research, 2013
Spontaneous lytic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) occurs at a low rate in latently infected cells in disease and culture. This suggests imperfect epigenetic maintenance of viral transcription programs, perhaps due to variability in chromatin structure at specific loci across the population of KSHV episomal genomes.
Darst, Russell P., Haecker, Irina, Pardo, Carolina E., Renne, Rolf, Kladde, Michael P.   +4 more
openaire   +2 more sources