Results 51 to 60 of about 14,230 (249)

Reactivation of Epstein-Barr virus lytic cycle by histone deacetylase inhibitors [PDF]

, 2015
Epstein-Barr virus (EBV) is closely associated with certain lymphoid and epithelial malignancies such as Burkitt lymphoma, nasopharyngeal carcinoma (NPC) and gastric carcinoma (GC).
Chiang, AKS, Hui, KF
core   +1 more source

Upper Airway Obstruction due to Kaposi Sarcoma—Presenting Sign of HIV: Case Report and Review

The Laryngoscope, EarlyView.
This study presents a case of undiagnosed HIV presenting with Kaposi sarcoma (KS) of the head and neck with acute upper airway obstruction (UAO) and provides an updated scoping literature review to examine the patient characteristics, lesion characteristics, interventions, and outcomes of KS cases with UAO from the pharynx, larynx, and/or trachea.
Zachary A. Wykoff, Logan F. McColl, Robert A. Baiocchi, Matthew O. Old   +3 more
wiley   +1 more source

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

Frontiers in Microbiology, 2012
Kaposi’s Sarcoma is a highly vascularized tumor supporting large amounts of neo-angiogenesis. The major cell type in KS tumors is the spindle cell, a cell that expresses markers of lymphatic endothelium. KSHV, the etiologic agent of KS, is found in the
Terri A. DiMiao, Michael eLagunoff
doaj   +1 more source

The KSHV ORF20 Protein Interacts with the Viral Processivity Factor ORF59 and Promotes Viral Reactivation

Microbiology Spectrum, 2021
Upon Kaposi’s Sarcoma-associated herpesvirus (KSHV) lytic reactivation, rapid and widespread amplification of viral DNA (vDNA) triggers significant nuclear reorganization.
D. Hoffman, W. Rodriguez, D. Macveigh-Fierro, J. Miles, M. Muller   +4 more
doaj   +1 more source

Prevalence of infection with human herpesvirus 8/Kaposi's sarcoma herpesvirus in rural South Africa [PDF]

, 1999
Objective. To determine prevalence of infection with human herpesvirus 8 (HHV-8)/Kaposi's sarcoma herpesvirus (KSHV) and to gain some insight into possible transmission dynamics of this novel virus in South Africa. Methods.
Gilks, C.F., Schulz, T.F., Sheldon, J., Wilkinson, D.   +3 more
core  

KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain [PDF]

, 2016
Background: Kaposi's sarcoma-associated herpesvirus (KSHV) glycoprotein B (gB) is not only expressed on the envelope of mature virions but also on the surfaces of cells undergoing lytic replication.
A Georgoulis, A Oppelt, BT Ning, C Bandyopadhyay, C Sun, D Lu, D Murray, DA Higuchi, DG Menter, E Rossi, ES Chhabra, F Angius, F Nakamura, FZ Wang, H Abe, H Doppler, HH Krishnan, HM Verheul, Hosni A. M. Hussein, HS Selistre-de-Araujo, I Limam, J Cau, J Chen, J Kim, J Lartigue de, J Li, JJ Calvete, JW Lee, K Eto, K Moissoglu, KJ Sepp, L Zhang, Lia R. Walker, LR Walker, M Chen, M May, M Onishi, N Sharma-Walia, NL Malinin, OF Dyson, OF Dyson, OF Dyson, PP Naranatt, R Karlsson, R Keil, RS Piotrowicz, S Abraham, SA Morad, SA Rezaee, Shaw M. Akula, SM Akula, SM Akula, SM Akula, ST Ong, T Geback, Y Kikkawa   +55 more
core   +1 more source

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

The FEBS Journal, EarlyView.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu, Noemi Nagy, Carlos Mario Ayala‐Torres, Maria G. Masucci   +3 more
wiley   +1 more source

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays [PDF]

, 2010
Basic-region leucine-zipper transcription factors (bZIPs) contain a segment rich in basic amino acids that can bind DNA, followed by a leucine zipper that can interact with other leucine zippers to form coiled-coil homo- or heterodimers.
Acharya A., Adya N., Amoutzias G. D., Basbous J., Bos T. J., Brown A. C., Campbell K. M., Chang Y. N., Chen W.-J., Chen Y. H., Countryman J., Cowell I. G., Daury L., Doi M., Ellison T. J., Gaudray G., Gerhard D. S., Grigoryan G., Hai T., Harbury P. B., Hardwick J. M., Hicks M. R., Hicks M. R., Hivin P., Hogan M., R., Hoover D. M., Huguier S., Ikushima S., Kataoka K., Kataoka K., Kataoka K., Katsuoka F., Kerppola T. K., Kuhlmann A.-S., Kutok J. L., Kvansakul M., Lai C.-K., Lefort S., Lemasson I., Levy A. M., Levy A. M., Lin S.-F., Lu R., Matsumoto J., Mesnard J. M., Moitra J., Nair V., Newman J. R. S., Oikarinen J., Parkin S. E., Petosa C., Pouponnot C., Qian Z., Qian Z., Rauscher F. J., Rossetto C., Ryseck R. P., Satou Y., Schepers A., Sinclair A. J., Suchodolski P. F., Thebault S., Thomas F. S., Ubeda M., van Straaten F., Vinson C. R., Vogt P. K., Witt A. E., Wu F. Y., Wu F. Y.   +69 more
core   +1 more source

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

HIV Medicine, EarlyView.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre, Antoine Gross, Alain Makinson   +2 more
wiley   +1 more source

The status of CMV as a human pathogen. [PDF]

, 2009
Cytomegalovirus (CMV) is a common infectious agent which is well adapted to its host. Following primary infection, which is almost always asymptomatic in people with normal immunity, the virus establishes latency at sites which are unknown.
Griffiths, PD, Grundy, JE
core   +2 more sources