Results 81 to 90 of about 12,565 (224)

An Optimized Protocol for the Generation of iPSC Lines from Lymphoblastoid Cell Lines Using the Non‐integrative Sendai Virus

Current Protocols, Volume 6, Issue 3, March 2026.
Abstract The choice of cell source for generating induced pluripotent stem cells (iPSCs) is influenced by several factors, including accessibility, reprogramming efficiency, and the invasiveness of the cell collection procedure. Traditional sources such as skin fibroblasts or peripheral blood mononuclear cells often require invasive sampling, which can
Laurie Martineau, Isabella Bienjonetti, Sabrina Bellenfant, Jack Puymirat, François Gros‐Louis   +4 more
wiley   +1 more source

KSHV and Human Diseases: Beyond KS, PEL and MCD

Microorganisms
Kaposi’s Sarcoma-associated herpesvirus (KSHV) has been etiologically linked to several human cancers, including Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). However, recent studies suggest that KSHV
Caroline Grace Firmin, Lu Dai, Zhiqiang Qin   +2 more
doaj   +1 more source

Immune reconstitution inflammatory syndrome, human herpesvirus 8 viremia, and HIV-associated multicentric Castleman disease

International Journal of Infectious Diseases, 2016
Kaposi's sarcoma and multicentric Castleman Disease are HIV-related disease processes that are associated with human herpesvirus 8 (HHV-8) infection.
Marc O. Siegel, Sanaz Ghafouri, Ravi Ajmera, Gary L. Simon   +3 more
doaj   +1 more source

Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma

Journal of Immunology Research, 2020
Kaposi’s sarcoma (KS) is an angioproliferative malignancy whose associated etiologic agent is the Kaposi’s sarcoma-associated herpesvirus (KSHV). KS is the most prevalent malignancy among HIV-infected individuals globally and is considered an AIDS ...
Owen Ngalamika, Sody Munsaka
doaj   +1 more source

Histological variants of cutaneous Kaposi sarcoma [PDF]

, 2008
This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e.
Wayne Grayson, Liron Pantanowitz
core   +1 more source

Unveiling the Immunopharmacological Mechanisms of Biejiajian Pills (BJJP) Underlying the Treatment of Hepatic Fibrosis: Insights From Network Pharmacology and Experimental Validation

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study employed an integrated workflow combining network pharmacology, machine learning, molecular docking, UHPLC‐HRMS, and in vivo validation. The core design aimed to identify key compounds and signature genes of BJJP against HF, explore their immune‐related mechanisms, and verify the therapeutic targets and pathways through experimental ...
Chan Mo, Zhuolin Wei, Jinnan He, Yuan Liu, Jiaorong Zheng, Min Hong, Yuhong Song   +6 more
wiley   +1 more source

Development of KSHV vaccine platforms and chimeric MHV68-K-K8.1 glycoprotein for evaluating the in vivo immunogenicity and efficacy of KSHV vaccine candidates

mBio
Kaposi’s sarcoma-associated herpesvirus (KSHV)/human herpesvirus 8 is an etiological agent of Kaposi’s Sarcoma, multicentric Castleman’s disease, and primary effusion lymphoma. Considering the high seroprevalence reaching up to 80% in sub-Saharan Africa,
Wan-Shan Yang, Dokyun Kim, Soowon Kang, Chih-Jen Lai, Inho Cha, Pei-Ching Chang, Jae U. Jung   +6 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 promotes cell proliferation and migration by upregulating DNMT1 via STAT3 activation.

PLoS ONE, 2014
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically associated with Kaposi's sarcoma (KS), the most common AIDS-related malignancy. KSHV vIL-6 promotes KS development, but the exact mechanisms remain unclear. Here, we reported that KSHV vIL-6
Jing Wu, Yuqiao Xu, Dongping Mo, Peijun Huang, Ruihong Sun, Lei Huang, Shiyang Pan, Jian Xu   +7 more
doaj   +1 more source

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays [PDF]

, 2010
Basic-region leucine-zipper transcription factors (bZIPs) contain a segment rich in basic amino acids that can bind DNA, followed by a leucine zipper that can interact with other leucine zippers to form coiled-coil homo- or heterodimers.
Acharya A., Adya N., Amoutzias G. D., Basbous J., Bos T. J., Brown A. C., Campbell K. M., Chang Y. N., Chen W.-J., Chen Y. H., Countryman J., Cowell I. G., Daury L., Doi M., Ellison T. J., Gaudray G., Gerhard D. S., Grigoryan G., Hai T., Harbury P. B., Hardwick J. M., Hicks M. R., Hicks M. R., Hivin P., Hogan M., R., Hoover D. M., Huguier S., Ikushima S., Kataoka K., Kataoka K., Kataoka K., Katsuoka F., Kerppola T. K., Kuhlmann A.-S., Kutok J. L., Kvansakul M., Lai C.-K., Lefort S., Lemasson I., Levy A. M., Levy A. M., Lin S.-F., Lu R., Matsumoto J., Mesnard J. M., Moitra J., Nair V., Newman J. R. S., Oikarinen J., Parkin S. E., Petosa C., Pouponnot C., Qian Z., Qian Z., Rauscher F. J., Rossetto C., Ryseck R. P., Satou Y., Schepers A., Sinclair A. J., Suchodolski P. F., Thebault S., Thomas F. S., Ubeda M., van Straaten F., Vinson C. R., Vogt P. K., Witt A. E., Wu F. Y., Wu F. Y.   +69 more
core   +1 more source

Kaposi‘s Sarcoma-Associated Herpesvirus and Innate Immunity [PDF]

Future Virology, 2010
Kaposi's sarcoma-associated herpesvirus (KSHV) is the most recently discovered human herpesvirus, first isolated and identified from a Kaposi's sarcoma lesion in 1994. It is the etiological agent of Kaposi's sarcoma, a vascular lesion that is the predominant cancer among AIDS patients. KSHV is also the primary etiological agent of two B-cell lymphomas,
John A, West, Blossom, Damania
openaire   +2 more sources