Results 171 to 180 of about 5,815 (206)

The Role of SARS-CoV-2 Nucleocapsid Protein in Host Inflammation. [PDF]

Viruses
Cao Y, Wang Y, Huang D, Tan YJ.
europepmc   +1 more source

TDP-43: unveiling the hidden key to cellular fate decisions. [PDF]

Cell Commun Signal
Liu B, Chen X, Wang J, Chen J, Zhao B, Jin X, Jiang M, Wang J, Liao W, Yang B, Geng X.   +10 more
europepmc   +1 more source

Phytophthora capsici carries and differentially expresses genes for the RNA interference pathway. [PDF]

PLoS One
Sevillano-Serrano J, Rojas-Rojas FU, Méndez-Bravo A, Calderón-Cortés N, Shimada-Beltrán H, Vega-Arreguín J.   +5 more
europepmc   +1 more source

The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation. [PDF]

J Biol Chem
Zhu B, Ouda R, An N, Tanaka T, Kobayashi KS.   +4 more
europepmc   +1 more source

Karyopherin abnormalities in neurodegenerative proteinopathies [PDF]

Brain, 2021
Neurodegenerative proteinopathies are characterized by progressive cell loss that is preceded by the mislocalization and aberrant accumulation of proteins prone to aggregation.
Terouz Pasha, Anna Zatorska, Daulet Sharipov   +2 more
exaly   +5 more sources

Nuclear import by karyopherin-βs: Recognition and inhibition

Biochimica Et Biophysica Acta - Molecular Cell Research, 2011
Proteins in the karyopherin-β family mediate the majority of macromolecular transport between the nucleus and the cytoplasm. Eleven of the 19 known human karyopherin-βs and 10 of the 14S.
Yuh Min Chook
exaly   +4 more sources

Some of the next articles are maybe not open access.

Related searches:

Karyopherin-mediated nucleocytoplasmic transport

Nature Reviews Molecular Cell Biology, 2022
Efficient and regulated nucleocytoplasmic trafficking of macromolecules to the correct subcellular compartment is critical for proper functions of the eukaryotic cell. The majority of the macromolecular traffic across the nuclear pores is mediated by the Karyopherin-β (or Kap) family of nuclear transport receptors.
Casey E. Wing, Ho Yee Joyce Fung, Yuh Min Chook   +2 more
openaire   +2 more sources

The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation [PDF]

International Journal of Cancer, 2009
AbstractThe Karyopherin proteins are involved in nucleo‐cytoplasmic trafficking and are critical for protein and RNA subcellular localization. Recent studies suggest they are important in nuclear envelope component assembly, mitosis and replication. Since these are all critical cellular functions, alterations in the expression of the Karyopherins may ...
Pauline J Van Der Watt, Denver T Hendricks, M Iqbal Parker   +2 more
exaly   +3 more sources

X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking

Journal of Molecular Biology, 2020
International audienceHere, we describe the crystal structures of two distinct isoforms of ligand-free human karyopherin RanBP5 and investigate its global propensity to interact with influenza A virus polymerase.
Christopher Swale, Bruno da Costa, Laura Sedano   +2 more
exaly   +2 more sources

Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin α

Structure, 2000
Background: Karyopherin α (importin α) is an adaptor molecule that recognizes proteins containing nuclear localization signals (NLSs). The prototypical NLS that is able to bind to karyopherin α is that of the SV40 T antigen, and consists of a short ...
Elena Conti, John Kuriyan
exaly   +2 more sources