The Long‐term Efficacy of Total Knee Arthroplasty on End‐stage Kashin–Beck Disease of the Knee in Highland Tibetan Areas Patients: A Retrospective Study with 10‐Year Follow‐up [PDF]
Orthopaedic SurgeryObjective Despite the established success of total knee arthroplasty (TKA) with end‐stage osteoarthritis, there is a notable scarcity of research on its long‐term outcomes in individuals suffering from end‐stage Kashin–Beck disease (KBD).
Haocheng Sun +5 more
doaj +4 more sources
A study on atypical Kashin–Beck disease: an endemic ankle arthritis [PDF]
Journal of Orthopaedic Surgery and Research, 2023 Background To study the epidemiological characteristics of atypical Kashin–Beck disease cases without characteristic hand lesions such as interphalangeal joint enlargement and brachydactyly and the characteristics of ankle joint lesions.
Fang Qi +4 more
doaj +3 more sources
Effects of selenium and iodine on Kashin-Beck disease: an updated review [PDF]
Frontiers in NutritionKashin-Beck disease (KBD) is an endochondral osteogenesis disorder characterised by epiphysis damage and secondary deformable arthropathy induced by multiple external factors, among which selenium (Se) and iodine deficiency are important influencing ...
Lin Liu, Pan Luo, Pengfei Wen, Peng Xu
doaj +3 more sources
Identification of energy metabolism and m6A-related gene clusters in Kashin-Beck disease based on bioinformatics analysis [PDF]
BMC Musculoskeletal DisordersKashin-Beck disease (KBD) is a chronic and debilitating osteoarthropathy predominantly affecting populations in certain endemic regions. Despite extensive research, the underlying mechanisms of KBD remain poorly understood.
Ao Zhou +6 more
doaj +3 more sources
Disease and Economic Burden of Kashin-Beck Disease - China, 2021. [PDF]
China CDC WklyWhat is already known about this topic? Kashin-Beck disease (KBD) is a chronic and degenerative osteoarthropathy characterized by cartilage degeneration.
Cui S +13 more
europepmc +4 more sources
Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China [PDF]
Arthritis Research & Therapy, 2022 Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning +15 more
doaj +3 more sources
Identification of N-Glycoproteins of Knee Cartilage from Adult Osteoarthritis and Kashin-Beck Disease Based on Quantitative Glycoproteomics, Compared with Normal Control Cartilage [PDF]
Cells, 2022 Glycoproteins are involved in the development of many diseases, while the type and content of N-glycoproteins in the cartilage of osteoarthritis (OA) and Kashin–Beck disease (KBD) are still unclear.
Jing Han +10 more
doaj +3 more sources
A comparative metabolomic analysis reveals the metabolic variations among cartilage of Kashin-Beck disease and osteoarthritis [PDF]
Bone & Joint ResearchAims: The metabolic variations between the cartilage of osteoarthritis (OA) and Kashin-Beck disease (KBD) remain largely unknown. Our study aimed to address this by conducting a comparative analysis of the metabolic profiles present in the cartilage of ...
Hong Chang +9 more
doaj +3 more sources
Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease [PDF]
Frontiers in Cell and Developmental BiologyObjectiveKashin-Beck disease (KBD) is a nutrition-related osteoarthropathy characterized by excessive apoptosis and matrix destruction. Micronutrient selenium (Se) deficiency is recognized as a major environmental risk factor.
Di Zhang +5 more
doaj +3 more sources
Differential expression of cyclins CCNB1 and CCNG1 is involved in the chondrocyte damage of kashin-beck disease [PDF]
Frontiers in Genetics, 2022 The purpose of this study was clarify the relationship between the differential expression of cyclins CCNB1 and CCNG1 and chondrocyte damage in Kashin-Beck disease. Systematic review and high-throughput sequencing of chondrocytes derived from Kashin-Beck
Kaidiriye Setiwalidi +20 more
doaj +2 more sources