Results 51 to 60 of about 58,318 (161)
BMC Musculoskeletal Disorders, 2012 Background Kashin-Beck Disease (KBD) is an endemic osteochondropathy. Mycotoxins are believed to play an important role in the pathogenesis of KBD. Because the molecular mechanism of mycotoxin-induced cartilage lesions remains unclear, there is not ...
Zhang Feng +5 more
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Proteoglycan metabolism, cell death and Kashin-Beck Disease [PDF]
Glycoconjugate Journal, 2012 Kashin-Beck Disease (KBD) is an endemic, chronic and degenerative osteoarthropathy principally occurring in children. The characteristic pathological change of KBD is chondrocyte necrosis in hyaline articular cartilage. Proteoglycans are one of the major components in the extracellular matrix of articular cartilage, and disrupted proteoglycan ...
Li, Siyuan +3 more
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Osteoarthritis Deformans Endemica: Etiology, Diagnosis, Treatment, Prevention
Bolʹ, Sustavy, Pozvonočnik, 2012 The paper deals with generalization of historical, epidemiological, etiologic, diagnostic, preventive and therapeutic data of osteoarthritis deformans endemica (Kashin — Beck disease). Taking into account the growing trend of deterioration of the current
T.V. Frolova +3 more
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The prevalence of mycotoxins in Kashin-Beck disease [PDF]
International Orthopaedics, 2001 Mycotoxins are naturally occurring toxic chemical compounds produced by fungi infesting agricultural crops both during their growth and storage. Such secondary metabolites, when ingested, can produce toxic syndromes in humans. As it has been suggested that mycotoxins might be involved in the development of Kashin-Beck disease (KBD), we undertook a ...
Haubruge, Éric +12 more
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Kashin-Beck disease and iodine deficiency in Tibet [PDF]
International Orthopaedics, 2001 We evaluated iodine and selenium status in 575 children between 5 and 15 years with Kashin-Beck disease from endemic and non-endemic areas. Of these 267 (46%) children had goiter. The proportion of subjects with goiter was higher in the villages with Kashin-Beck disease than in the control village. In the villages with Kashin-Beck disease, 105 (23%) of
Moreno-Reyes, R. +9 more
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Kashin-Beck disease: a historical overview [PDF]
International Orthopaedics, 2001 In 1919, the first report on Kashin-Beck disease (KBD) made by a Japanese doctor described an endemic occurrence in the northern district of Korea. In the 1930s, Dr. Takamori and his colleagues at Manchuria Medical College produced a series of reports on its endemiology, clinical and roentgenological findings observed in the north-eastern district of ...
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Arthritis Research & Therapy, 2018 Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar clinical manifestations and pathological changes to articular cartilage with KBD ...
Yan Wen +10 more
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Kashin-Beck disease involving the ankles
Radiology Case Reports, 2011 We present a case of Kashin-Beck Disease primarily affecting the ankles. Our findings are consistent with other reports of the symptoms, incidence, and progression of these diseases. At this time, our patient has chosen conservative treatment, but is considering eventual osteoarticular allografts.
Niebulski, Hannah Z. +1 more
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BMC Public Health, 2021 Background Kashin-Beck disease (KBD) is one of the major endemic diseases in China, which severely impacts the physical health and life quality of people.
Jing Wang +5 more
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Cytotoxic Properties of HT-2 Toxin in Human Chondrocytes: Could T3 Inhibit Toxicity of HT-2?
Toxins, 2019 Thyroid hormone triiodothyronine (T3) plays an important role in coordinated endochondral ossification and hypertrophic differentiation of the growth plate, while aberrant thyroid hormone function appears to be related to skeletal malformations ...
Feng’e Zhang +6 more
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