Results 121 to 130 of about 12,768 (245)

Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.

, 2012
BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Hallbauer, UM, Hesseling, AC, Rose, PC, Schaaf, HS, Seddon, JA   +4 more
core   +1 more source

KatG protein analysis: Misfolding and drug resistance

Tuberculosis is caused by Mycobacterium tuberculosis and is commonly treated with antibiotics. Recently, drug resistance to isoniazid, the most common drug utilized to treat tuberculosis, has been becoming more prevalent. Hence, this study aimed to analyze factors affecting isoniazid resistance using a bioinformatics pipeline.
Daniel Ryan Fugaha, Juan Lorell, Dhannyo Putta, Dennis Lunnoto, Arli Aditya Parikesit   +4 more
openaire   +1 more source

Prevalence of katG and inhA mutations associated with isoniazid resistance in Mycobacterium tuberculosis clinical isolates in Cameroon

BMC Microbiology
Background The acquisition of isoniazid (INH) resistance is alarming, considering its importance as a key drug that forms the core of multidrug treatment regimens for tuberculosis (TB). Genetic mutations in the katG and inhA promoter regions play crucial
Vanessa Ninkeh Nono, Edouard Akono Nantia, Awelani Mutshembele, Sorelle Nguimfack Teagho, Yannick Willy Kamdem Simo, Brenda Shile Takong, Yvonne Josiane Djieugoue, Yannick Patrick Assolo, Suzanne Magloire Ongboulal, Stanley Nkemnji Awungafac, Sara Eyangoh, Eric Mensah, Ndivhuho Agnes Makhado, Valerie Flore Donkeng Donfack   +13 more
doaj   +1 more source

KatG as Counterselection Marker for Nontuberculous Mycobacteria

Antimicrobial Agents and Chemotherapy, 2020
Gagliardi, Aron, Selchow, Petra, Luthra, Sakshi, Schäfle, Daniel, Schulthess, Bettina, Sander, Peter   +5 more
openaire   +4 more sources

Regulation of catalase–peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis [PDF]

, 2001
Alexander S. Pym, Pilar Domenech, Nadine Honoré, Jian Song, Vojo Deretić, Stewart T. Cole   +5 more
openalex   +1 more source

The Susceptibility of katG Ser315Thr Mycobacterium tuberculosis mutant Against Anti Tuberculosis Drugs

Indonesian Journal of Biotechnology, 2016
Mycobacterium tuberculosis resistant strains is a matter of great concern for TB control Program since nocure for some multi drug resistance TB (MDR-TB) cases.
Ning Rintiswati, Praseno P
doaj  

Crystal structure of the catalase–peroxidase KatG W78F mutant from Synechococcus elongatus PCC7942 in complex with the antitubercular pro‐drug isoniazid [PDF]

, 2014
Saori Kamachi, Kei Hirabayashi, Masahiro Tamoi, Shigeru Shigeoka, Toshiji Tada, Kei Wada   +5 more
openalex   +1 more source

Characterization of katG, inhA, rpoB and pncA in Mycobacterium tuberculosis isolates from MDR-TB risk patients in Thailand

, 2020
Krairerk Suthum, Worada Samosornsuk, Seksun Samosornsuk   +2 more
openalex   +2 more sources

Mutations in katG and inhA genes of isoniazid-resistant and -sensitive clinical isolates of Mycobacterium tuberculosis from cases of pulmonary tuberculosis and their association with minimum inhibitory concentration of isoniazid [PDF]

, 2016
Indu Jaiswal, Amita Jain, Pooja Singh, S K Verma, Shantanu Prakash, Pratima Dixit, Suryakant, Mastan Singh   +7 more
openalex   +1 more source

Epidemiologic Characterization of Culture Positive Mycobacterium tuberculosis Patients by katG-gyrA Principal Genetic Grouping [PDF]

, 2009
Carolyn Z. Grimes, Larry D. Teeter, Lu Y. Hwang, Edward A. Graviss   +3 more
openalex   +1 more source