Results 101 to 110 of about 8,860 (214)
PURIFIKASI PROTEIN KatG Mycobacterium tuberculosis ISOLAT KLINIS LOKAL (H37Rv) DAN UJI IMUNOGENISITAS SEBAGAI KANDIDAT VAKSIN TB [PDF]
, 2016 Tuberkulosis (TB) merupakan masalah kesehatan utama di seluruh dunia yang menyebabkan sejumlah besar kematian, disebabkan oleh infeksi Mycobacterium tuberculosis.
RIZAL AKBAR, 081424253003
core +1 more source
International Journal of Mycobacteriology, 2018 Background: Effective management of multidrug-resistant tuberculosis (MDR-TB) requires cost-effective and rapid screening of rifampicin (RIF) and isoniazid (INH) resistance.
Sanjay Singh Negi +6 more
doaj +1 more source
Oxidative stress detection with Escherichia coli harboring a katG'::lux fusion
Applied and Environmental Microbiology, 1996 A plasmid containing a transcriptional fusion of the Escherichia coli katG promoter to a truncated Vibrio fischeri lux operon (luxCDABE) was constructed. An E. coli strain bearing this plasmid (strain DPD2511) exhibited low basal levels of luminescence, which increased up to 1,000-fold in the presence of hydrogen peroxide, organic peroxides, redox ...
Belkin, S. +4 more
openaire +3 more sources
Role of the Oxyferrous Heme Intermediate and Distal Side Adduct Radical in the Catalase Activity of Mycobacterium Tuberculosis Katg Revealed by the W107F Mutant [PDF]
, 2009 Catalase-peroxidase (KatG) is essential in Mycobacterium tuberculosis for oxidative stress management and activation of the antitubercular pro-drug isoniazid.
Magliozzo, Richard S. +6 more
core +1 more source
Indonesian Journal of Biotechnology, 2015 Mycobacterium tuberculosis strains resistance to INH is mainly caused by the alteration in several genesencoding the molecular targets. Mutation of katG at codon 315 especially Ser315Thr are responsible forINH resistance in a large proportion of TB cases.
Ning Rintiswati +3 more
doaj
PLoS ONE, 2015 BackgroundDrug-resistant tuberculosis (TB) remains extremely difficult to treat because there are often few remaining active medications and limited diagnostic options to detect resistance.
Abraham J Niehaus +4 more
doaj +1 more source
KatG protein analysis: Misfolding and drug resistance
Tuberculosis is caused by Mycobacterium tuberculosis and is commonly treated with antibiotics. Recently, drug resistance to isoniazid, the most common drug utilized to treat tuberculosis, has been becoming more prevalent. Hence, this study aimed to analyze factors affecting isoniazid resistance using a bioinformatics pipeline.
Daniel Ryan Fugaha +4 more
openaire +1 more source
, 1997 Oxidative stress is an accumulation of reactive oxygen species which can be toxic to the cell. In Escherichia coli, the expression of katG, encoding catalase, hydroperoxidase I, is induced in response to oxidative stress.
Glater, Elizabeth +1 more
core +1 more source
ADMET and DMPKBackground and purpose: Multidrug-resistant tuberculosis (MDR-TB) remains a significant challenge in tuberculosis (TB) treatment, driven by simultaneous mutations in the rpoB and katG genes that confer resistance to rifampicin and isoniazid.
Dika Apriliana Wulandari +6 more
doaj +1 more source
KatG as Counterselection Marker for Nontuberculous Mycobacteria
Antimicrobial Agents and Chemotherapy, 2020 Gagliardi, Aron +5 more
openaire +5 more sources