Results 121 to 130 of about 8,860 (214)

Impacts of the oxidizable scaffold of catalase-peroxidase (KatG): Modulation of a heme peroxidase for catalytic versatility

, 2021
Catalase-peroxidase (KatG) is an antioxidant protein that plays a key role in the degradation of H2O2 for pathogenic and non-pathogenic bacteria and lower eukaryotes.
Krewall, Jessica
core  

吉林省耐多药结核分枝杆菌rpoB及katG基因突变特征分析

Zhongguo shiyan zhenduanxue, 2017
目的分析吉林省耐多药结核分枝杆菌临床分离株rpoB、katG基因突变特点,为建立本省快速耐多药检测方法提供参考。方法对吉林省耐多药结核分枝杆菌菌株扩增rpoB、katG基因测序后比对分析。结果耐多药结核分枝杆菌rpoB、katG基因的突变率分别为83.53%和70.6%,突变类型包括点突变、联合突变和缺失。在rpoB基因中,82.30%突变发生在RRDR区域,最常见突变位点为rpoB 531、rpoB 526、rpoB 516。KatG基因突变率为70.6%,最常见突变位点为katG315 ...
张炜煜, 杨修军, 王慧, 张立夫, 李可维   +4 more
doaj  

Mutations leading to drug-resistant Mycobacterium tuberculosis infection in Ukraine

Open Medicine, 2010
Antonenko Kate, Kresyun Valentin, Antonenko Peter   +2 more
doaj   +1 more source

Life without KatG

Trends in Microbiology, 1996
openaire   +2 more sources

Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Tuberculosis and Respiratory Diseases, 2019
Background The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results of isoniazid (INH) and prothionamide (Pto).
Joo Hee Lee, M.D., Kyung-Wook Jo, M.D., Ph.D., Tae Sun Shim, M.D., Ph.D.   +2 more
doaj  

Rapid simultaneous detection of <i>katG</i> S315T and <i>rpoB</i> S531L mutations for molecular screening of multidrug-resistant tuberculosis using a dual LAMP-lateral flow assay. [PDF]

Microbiol Spectr
Ckumdee J, Santiwatanakul S, Vutipow N, Kaewphinit T.   +3 more
europepmc   +1 more source

Real-world evaluation of the FluoroType MTBDR 2.0 assay for detection of rifampicin and isoniazid resistance-conferring mutations in <i>Mycobacterium tuberculosis</i> complex clinical isolates. [PDF]

Microbiol Spectr
Ferreira FMdA, Brandão AP, Massanti TB, Rego ACdS, Ferrazoli L, Chimara E, de Oliveira RS, Pinhata JMW.   +7 more
europepmc   +1 more source

Development and Preliminary Evaluation of RR-TB GoldDx and Hr-TB GoldDx: Rapid Visual RPA-Gold Nanoparticle Assays for Detecting Rifampicin- and Isoniazid-Resistance-Associated Mutations in <i>Mycobacterium tuberculosis</i>. [PDF]

Biosensors (Basel)
Wattananandkul U, Saikaew S, Sangboonruang S, Pongsararuk R, Srilohasin P, Butr-Indr B, Intorasoot S, Tharinjaroen CS, Semakul N, Arunothong S, Chaiprasert A, Tragoolpua K.   +11 more
europepmc   +1 more source

Translating drug-resistant tuberculosis surveillance into molecular-biophotonic diagnostic innovation in rural Eastern Cape, South Africa. [PDF]

Front Tuberc
Sineke N, Sabisa K, Dlatu N, Ombinda-Lemboumba S, Apalata T, Faye LM.   +5 more
europepmc   +1 more source

Rapid Extensively Drug-Resistant (XDR) TB Diagnosis: An In-House DNA Biochip for Drug Resistance Detection and Mutation Profiling of <i>Mycobacterium tuberculosis</i>. [PDF]

Can J Infect Dis Med Microbiol
Jain B, Kulkarni S, Baghel NS.
europepmc   +1 more source