Results 1 to 10 of about 30,063 (226)

Inhibin alpha-subunit (INHA) expression in adrenocortical cancer is linked to genetic and epigenetic INHA promoter variation. [PDF]

open access: yesPLoS ONE, 2014
Adrenocortical carcinoma (ACC) is a rare, but highly malignant tumor of unknown origin. Inhibin α-subunit (Inha) knockout mice develop ACCs following gonadectomy.
Johannes Hofland   +9 more
doaj   +8 more sources

INHA Acts as a Novel and Potential Biomarker in Lung Adenocarcinoma and Shapes the Immune-Suppressive Tumor Microenvironment

open access: yesTranslational Oncology, 2023
Background: INHA expression has been correlated with the development, growth, and progression of multiple cancer types. However, the biological role of INHA has not been investigated in patients with lung adenocarcinoma (LUAD).
Bo Cheng, Dizhi Jiang
exaly   +3 more sources

Computational evaluation of marine demospongiae sponges metabolites activity as mycolic acid biosynthesis inhibitors in Mycobacterium tuberculosis

open access: yesInternational Journal of Mycobacteriology, 2023
Background: Mycobacterium tuberculosis is a bacterium that has historically had a substantial impact on human health. Despite advances in understanding and management of tuberculosis (TB), the disease remains a crucial problem that necessitates ongoing ...
Abdullah R Alanzi
doaj   +1 more source

Association between INHA gene polymorphisms and litter size in Hainan black goats [PDF]

open access: yesPeerJ, 2023
Background The inhibin alpha (INHA) gene is one of the important genes affecting the reproductive traits of animals. Hainan black goats are the main goat breed in Hainan Island (China), whose development is limited by low reproductive performance ...
Zhengyu Bian   +5 more
doaj   +2 more sources

Julien Poinssot and His Descendants

open access: yesRevista de Historiografía, 2021
This paper discusses the scientific lives of Julien, Louis and Claude Poinssot (grandfather, father and son) and their important contribution to the study of ancient religions in North Africa, especially in Tunisia, including their intense engagement ...
María Fernández Portaencasa
doaj   +1 more source

Anti-tubercular activity and molecular docking studies of indolizine derivatives targeting mycobacterial InhA enzyme

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
A series of 1,2,3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were screened for in vitro whole-cell anti-tubercular activity against the susceptible H37Rv and multidrug-resistant (MDR) Mycobacterium tuberculosis (MTB) strains.
Katharigatta N. Venugopala   +21 more
doaj   +1 more source

Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance

open access: yesJournal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2023
Background: High-dose isoniazid is recommended in the 9–12 months short-course regimen for multidrug-resistant tuberculosis with inhA mutation. However, there is insufficient evidence to support the assumption of genotypic-phenotypic concordance.
Senamile Lale Ngema   +9 more
doaj   +1 more source

Evaluación de una vacuna de ADN y su péptido recombinante contra inhibina alfa (165-300) sobre la respuesta inmune y fertilidad en ratones

open access: yesNova Scientia, 2018
Se evalúo la vacuna de ADN (INHA-DNA) y su péptido recombinante (INHA-rec) contra inhibina alfa (INHA) sobre la respuesta inmune y la fertilidad en ratones. Dieciséis ratones Balb/c fueron divididos en dos grupos, 8 cada uno.
Carlos Luna-Palomera   +6 more
doaj   +3 more sources

Inhibin Alpha Expression in Human Tumors: A Tissue Microarray Study on 12,212 Tumors

open access: yesBiomedicines, 2022
As a result of its expression in corresponding normal cell types, inhibin alpha (INHA) is used as an immunohistochemical marker for adrenocortical neoplasms and testicular or ovarian sex cord stromal tumors.
Sören Weidemann   +24 more
doaj   +1 more source

Molecular Docking and Chemical Analysis of Alcohol Compounds (C16-C20) Bound to InhA Receptors as Mycobactericidal Candidates

open access: yesJurnal Kimia Sains dan Aplikasi, 2020
Tuberculosis (TB) is an infectious disease caused by a bacterium called Mycobacterium tuberculosis. TB infection spreads through the air and is more likely when using inappropriate disinfectants in medical and laboratory equipment related to TB research.
Muhammad Iqbal Shihab, Gita Syahputra
doaj   +1 more source

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