Results 11 to 20 of about 30,063 (226)

Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages. [PDF]

open access: yesPLoS ONE, 2011
Hemorrhagic meningitis is a fatal complication of anthrax, but its pathogenesis remains poorly understood. The present study examined the role of B.
Dhritiman V Mukherjee   +7 more
doaj   +2 more sources

Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA [PDF]

open access: yesLife Science Alliance, 2018
AN12855 is a novel cofactor-independent inhibitor of Mycobacterium tuberculosis InhA. AN12855 has potent activity against M. tuberculosis , good oral bioavailability, and comparable efficacy to isoniazid in infection models. New antitubercular agents are
Yi Xia   +23 more
doaj   +3 more sources

Inhibition of Mycobacterium tuberculosis InhA by 3-nitropropanoic acid [PDF]

open access: yes, 2021
3-Nitropropanoic acid (3NP), a bioactive fungal natural product, was previously demonstrated to inhibit growth of Mycobacterium tuberculosis. Here we demonstrate that 3NP inhibits the 2-trans-enoyl-acyl carrier protein reductase (InhA) from Mycobacterium
Nitima Suttipanta   +23 more
core   +1 more source

RNA-seq data on inha-/- vs. control (bmp15+/+;inha+/+).

open access: yes, 2023
RNA-seq data on inha-/- vs. control (bmp15+/+;inha+/+).
Xin Zhang (35492)   +7 more
core   +1 more source

RNA-seq data on bmp15-/-;inha-/- vs. control (bmp15+/+;inha+/+).

open access: yes, 2023
RNA-seq data on bmp15-/-;inha-/- vs. control (bmp15+/+;inha+/+).
Xin Zhang (35492)   +7 more
core   +1 more source

Transcriptome analysis of bmp15 and inha-deficient follicles.

open access: yes, 2023
(A) Heatmap of DGEs among four genotypes of bmp15 and inha mutants. The heatmap of bmp15-/-;inha-/- showed similar pattern to that of inha-/- but not bmp15-/-.
Xin Zhang (35492)   +7 more
core   +1 more source

The Cultural Heritage of Lviv Region: (Visions of Expert Environments) [PDF]

open access: yesСоціологія, 2022
The article is written on the empirical basis of 20 semi-structured in-depth interviews with architects, representatives of the tourism industry, and cultural managers, collected in March-June 2021.
Inha Kozlova
doaj   +1 more source

Phenotype analysis of single (gdf9-/- and inha-/-) and double mutants (gdf9-/-;inha-/-) at 90 dpf.

open access: yes, 2022
(A and B) Follicle composition in different genotypes. The follicles in gdf9-/- were arrested at PG stage. Although the PG-PV transition and yolk accumulation resumed in the double mutant (gdf9-/-;inha-/-), the vitellogenic growth could not proceed to ...
Bo Zhu (118038)   +7 more
core   +1 more source

Potentiating the Anti-Tuberculosis Efficacy of Peptide Nucleic Acids through Combinations with Permeabilizing Drugs

open access: yesMicrobiology Spectrum, 2022
The emergence of antimicrobial resistance warrants for the development of improved treatment approaches. In this regard, peptide nucleic acids (PNAs) have shown great promise, exhibiting antibiotic properties through the targeting of cellular nucleic ...
Karishma Berta Cotta   +2 more
doaj   +1 more source

Importance of Detection of Isoniazid and Rifampicin Mono Drug Resistance and Determining Rate of MDR-TB in Smear Positive Sputum Samples from a Tertiary Care Hospital of West U.P. India

open access: yesJournal of Pure and Applied Microbiology, 2019
Anti-tubercular therapy is one of the effective strategies used to control tuberculosis, so, a planned and accurate treatment regimen is of utmost importance, but number of cases are being treated as MDR on the basis of rifampicin mono resistance.
Sana Nudrat, Umar Farooq, Mazhar Maqsood
doaj   +1 more source

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