Results 31 to 40 of about 32,637 (272)

Kdr genotyping in Aedes aegypti from Brazil on a nation-wide scale from 2017 to 2018

Scientific Reports, 2020
Insecticide resistance is currently a threat to the control of Aedes agypti, the main vector of arboviruses in urban centers. Mutations in the voltage gated sodium channel (NaV), known as kdr (knockdown resistance), constitute an important selection ...
M. Melo Costa, K. B. Campos, Luiz Paulo Brito, Emmanuelle Roux, Cynara de Melo Rodovalho, D. F. Bellinato, J. B. Lima, A. Martins   +7 more
semanticscholar   +1 more source

Assessing the effects of Aedes aegypti kdr mutations on pyrethroid resistance and its fitness cost. [PDF]

PLoS ONE, 2013
Pyrethroids are the most used insecticide class worldwide. They target the voltage gated sodium channel (NaV), inducing the knockdown effect. In Aedes aegypti, the main dengue vector, the AaNaV substitutions Val1016Ile and Phe1534Cys are the most ...
Luiz Paulo Brito, Jutta G B Linss, Tamara N Lima-Camara, Thiago A Belinato, Alexandre A Peixoto, José Bento P Lima, Denise Valle, Ademir J Martins   +7 more
doaj   +1 more source

Multiplex PCR for simultaneous genotyping of kdr mutations V410L, V1016I and F1534C in Aedes aegypti (L.)

Parasites & Vectors, 2020
Background Knockdown resistance (kdr) is the main mechanism that confers resistance to pyrethroids and DDT. This is a product of non-synonymous mutations in the voltage-gated sodium channel (vgsc) gene, and these mutations produce a change of a single ...
Karina Villanueva-Segura, Gustavo Ponce-Garcia, Beatriz Lopez-Monroy, Esteban Mora-Jasso, Lucia Perales, Francisco J. Gonzalez-Santillan, Kevin Ontiveros-Zapata, Jesus A. Davila-Barboza, Adriana E. Flores   +8 more
doaj   +1 more source

Investigating insecticide resistance and knock-down resistance (kdr) mutation in Dielmo, Senegal, an area under long lasting insecticidal-treated nets universal coverage for 10 years

Malaria Journal, 2018
Background The use of insecticides, through indoor residual spraying and long-lasting insecticide-treated nets (LLINs), is essential to control malaria vectors.
Omar Thiaw, Souleymane Doucouré, Seynabou Sougoufara, Charles Bouganali, Lassana Konaté, Nafissatou Diagne, Ousmane Faye, Cheikh Sokhna   +7 more
doaj   +1 more source

Genome-wide Association Study Reveals New Loci Associated With Pyrethroid Resistance in Aedes aegypti

Frontiers in Genetics, 2022
Genome-wide association studies (GWAS) use genetic polymorphism across the genomes of individuals with distinct characteristics to identify genotype-phenotype associations.
Luciano V. Cosme, José Bento Pereira Lima, Jeffrey R. Powell, Ademir Jesus Martins, Ademir Jesus Martins   +4 more
doaj   +1 more source

Resistance to Permethrin, β-cyfluthrin, and Diazinon in Florida Horn Fly Populations

Insects, 2018
Horn flies, Haematobia irritans, a major cattle pest in the USA, cause substantial economic losses and current control methods rely heavily on insecticides.
Chris J. Holderman, Daniel R. Swale, Jeffery R. Bloomquist, Phillip E. Kaufman   +3 more
doaj   +1 more source

Malaria vectors in the Democratic Republic of the Congo: the mechanisms that confer insecticide resistance in Anopheles gambiae and Anopheles funestus

Malaria Journal, 2017
Background The Democratic Republic of the Congo (DRC) is characterized as a holoendemic malaria area with the main vectors being Anopheles funestus and members of the Anopheles gambiae complex.
Luisa Nardini, Richard H. Hunt, Yael L. Dahan-Moss, Nanette Christie, Riann N. Christian, Maureen Coetzee, Lizette L. Koekemoer   +6 more
doaj   +1 more source

Evidence for both sequential mutations and recombination in the evolution of kdr alleles in Aedes aegypti

PLoS Neglected Tropical Diseases, 2020
Background Aedes aegypti is a globally distributed vector of human diseases including dengue, yellow fever, chikungunya, and Zika. Pyrethroid insecticides are the primary means of controlling adult A.
Yinjun Fan, P. O'Grady, M. Yoshimizu, A. Ponlawat, P. Kaufman, J. G. Scott   +5 more
semanticscholar   +1 more source

Presence of the knockdown resistance (kdr) mutations in the head lice (Pediculus humanus capitis) collected from primary school children of Thailand

PLoS Neglected Tropical Diseases, 2020
Human head lice are blood-sucking insects causing an infestation in humans called pediculosis capitis. The infestation is more prevalent in the school-aged population.
Narisa Brownell, Sakone Sunantaraporn, K. Phadungsaksawasdi, Nirin Seatamanoch, Switt Kongdachalert, A. Phumee, P. Siriyasatien   +6 more
semanticscholar   +1 more source

ECSCR enhances KDR activation and promotes proteolysis of internalized KDR (LB160)

The FASEB Journal, 2014
The endothelial cell‐specific chemotaxis receptor (ECSCR) is a cell‐surface protein selectively expressed by endothelial cells (ECs), with roles in EC migration, apoptosis and proliferation. Our previous study showed that loss of ECSCR in primary ECs reduced tyrosine phosphorylation of vascular endothelial growth factor (VEGF) receptor 2/kinase insert ...
George Wilkinson, Sreenivas Kilari, Indulekha Remadevi, Baofeng Baofeng Zhao, Jing Pan, Robert Miao, Ramani Ramchandran, Paula North, Ming You, Nader Rahimi   +9 more
openaire   +1 more source